Invasive fungal infection is an under recognized and emerging global health threat.
Recently, the World Health Organization (WHO) released the first ever list of health …

Immunity to pathogens critically requires pattern-recognition receptors (PRRs) to trigger
intracellular signaling cascades that initiate and direct innate and adaptive immune …

In the last few decades, the AIDS pandemic and the significant advances in the medical
management of individuals with neoplastic and inflammatory conditions have resulted in a …

Abstract β-glucans, a group of polysaccharides exist in many organism species such as
mushrooms, yeasts, oats, barley, seaweed, but not mammalians, have a variety of biological …

Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

Activating innate immunity in a controlled manner is necessary for the development of next-
generation therapeutics. Adjuvants, or molecules that modulate the immune response, are …

New foods and natural biological modulators have recently become of scientific interest in
the investigation of the value of traditional medical therapeutics. Glucans have an important …

Yeast has been employed as an effective derived drug carrier as a unicellular
microorganism. Many research works have been devoted to the encapsulation of nucleic …

Dectin-1 is an innate immune pattern recognition receptor (PRR) that, through its ability to
bind β-glucans, is involved in the recognition of several pathogenic fungi. Dectin-1 can …

The limited number of oral vaccines currently approved for use in humans and veterinary
species clearly illustrates that development of efficacious and safe oral vaccines has been a …