Mechanobiology of collective cell behaviours

B Ladoux, RM Mège - Nature reviews Molecular cell biology, 2017 - nature.com
The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Physics of microswimmers—single particle motion and collective behavior: a review

J Elgeti, RG Winkler, G Gompper - Reports on progress in …, 2015 - iopscience.iop.org
Locomotion and transport of microorganisms in fluids is an essential aspect of life. Search
for food, orientation toward light, spreading of off-spring, and the formation of colonies are …

Motility-driven glass and jamming transitions in biological tissues

D Bi, X Yang, MC Marchetti, ML Manning - Physical Review X, 2016 - APS
Cell motion inside dense tissues governs many biological processes, including embryonic
development and cancer metastasis, and recent experiments suggest that these tissues …

Single and collective cell migration: the mechanics of adhesions

C De Pascalis… - Molecular biology of the …, 2017 - Am Soc Cell Biol
Chemical and physical properties of the environment control cell proliferation, differentiation,
or apoptosis in the long term. However, to be able to move and migrate through a complex …

A density-independent rigidity transition in biological tissues

D Bi, JH Lopez, JM Schwarz, ML Manning - Nature Physics, 2015 - nature.com
Cell migration is important in many biological processes, including embryonic development,
cancer metastasis and wound healing. In these tissues, a cell's motion is often strongly …

Hydrodynamics of soft active matter

MC Marchetti, JF Joanny, S Ramaswamy… - Reviews of modern …, 2013 - APS
This review summarizes theoretical progress in the field of active matter, placing it in the
context of recent experiments. This approach offers a unified framework for the mechanical …

ERK-mediated mechanochemical waves direct collective cell polarization

N Hino, L Rossetti, A Marín-Llauradó, K Aoki, X Trepat… - Developmental cell, 2020 - cell.com
During collective migration of epithelial cells, the migration direction is aligned over a tissue-
scale expanse. Although the collective cell migration is known to be directed by mechanical …

Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers

L Balasubramaniam, A Doostmohammadi, TB Saw… - Nature materials, 2021 - nature.com
Actomyosin machinery endows cells with contractility at a single-cell level. However, within a
monolayer, cells can be contractile or extensile based on the direction of pushing or pulling …

Physics of active jamming during collective cellular motion in a monolayer

S Garcia, E Hannezo, J Elgeti… - Proceedings of the …, 2015 - National Acad Sciences
Although collective cell motion plays an important role, for example during wound healing,
embryogenesis, or cancer progression, the fundamental rules governing this motion are still …

Sculpting tissues by phase transitions

PF Lenne, V Trivedi - Nature Communications, 2022 - nature.com
Biological systems display a rich phenomenology of states that resemble the physical states
of matter-solid, liquid and gas. These phases result from the interactions between the …