RNA-binding proteins (RBPs) play a critical role in the regulation of various RNA processes,
including splicing, cleavage and polyadenylation, transport, translation and degradation of …

Valvular heart disease is associated with significant morbidity and mortality and often the
result of congenital malformations. However, the prevalence is increasing in adults not only …

RNA-binding proteins control the metabolism of RNAs at all stages of their lifetime. They are
critically required for the post-transcriptional regulation of gene expression in a wide variety …

We performed a genome-wide association study (GWAS) of antibody levels in a multi-ethnic
group of 1071 healthy smallpox vaccine recipients. In Caucasians, the most prominent …

In vivo, RNA molecules are constantly accompanied by RNA binding proteins (RBPs), which
are intimately involved in every step of RNA biology, including transcription, editing, splicing …

p21, a cyclin-dependent kinase inhibitor, is necessary for proper control of the cell cycle and
premature senescence. Thus, p21 expression needs to be tightly controlled. In this study, we …

Abstract p63, a p53 family member, plays pivotal roles in epidermal development, aging,
and tumorigenesis. Thus, understanding how p63 expression is controlled has biological …

Pre–mRNAs are often processed in complex patterns in tissue-specific manners to produce
a variety of protein isoforms from single genes. However, mechanisms orchestrating the …

Hair cells in the inner ear and lateral lines are mechanosensitive receptor cells whose
development and function are tightly regulated. Several transcription factors as well as …

IFN is essential for hosts to defend against viral invasion, whereas it must be tightly
regulated to prevent hyperimmune responses. Fish mitochondrial antiviral signaling protein …