Pharmacological interventions targeting α-synuclein aggregation triggered REM sleep behavior disorder and early development of Parkinson's disease

L Du, X He, X Fan, X Wei, L Xu, T Liang, C Wang… - Pharmacology & …, 2023 - Elsevier
Rapid eye movement (REM) sleep behavior disorder (RBD) is a parasomnia characterized
by elevated motor behaviors and dream enactments in REM sleep, often preceding the …

New Paradigm in the Management of REM Sleep Behavior Disorder

A Rihawi, S Mashaqi, JK Lee-Iannotti… - Current Sleep Medicine …, 2023 - Springer
Abstract Purpose of Review Rapid eye movement (REM) behavior disorder (RBD) is a
complex parasomnia, with growing evidence showing that it represents a prodromal marker …

[HTML][HTML] Therapeutic effect of levodopa/carbidopa/entacapone on sleep disturbance in patients with Parkinson's disease

KW Park, S Jo, SH Lee, YS Hwang, D Lee… - Journal of Movement …, 2020 - ncbi.nlm.nih.gov
Objective To investigate the efficacy of levodopa/carbidopa/entacapone (LCE) at bedtime for
treating sleep disturbance in patients with Parkinson's disease (PD) with motor fluctuations …

[HTML][HTML] The cross-hemispheric nigrostriatal pathway prevents the expression of levodopa-induced dyskinesias

V Iyer, K Venkiteswaran, S Savaliya, CA Lieu… - Neurobiology of …, 2021 - Elsevier
Parkinson's disease (PD) is a neurodegenerative movement disorder that is routinely treated
with levodopa. Unfortunately, long-term dopamine replacement therapy using levodopa …

REM sleep without atonia and nocturnal body position in prediagnostic Parkinson's disease

F Dijkstra, N Reyn, B de Bruyn, K Van den Bossche… - Sleep Medicine, 2021 - Elsevier
Background Sleep disturbances are features of Parkinson's disease (PD), that can already
occur before PD diagnosis. The most investigated prodromal PD sleep disorder is REM …

Exploring the Causal Relationship Between Migraine and Insomnia Through Bidirectional Two-Sample Mendelian Randomization: A Bidirectional Causal …

D Ouyang, Y Liu, W Xie - Journal of Pain Research, 2024 - Taylor & Francis
Introduction The intricate relationship between migraine and insomnia has been a subject of
great interest due to its complex mechanisms. Despite extensive research, understanding …

Modeling polyurethane foam (PUF)-air partition coefficients for persistent organic pollutants using linear and non-linear chemometric methods

L Gu, T Zhu, M Chen - Journal of Environmental Chemical Engineering, 2021 - Elsevier
As an indispensable basic parameter in measuring the concentration of compounds by
passive air sampling (PAS) devices, the partition coefficient could be further employed in …

Optimization the treatment of motor fluctuations in various forms of Parkinson's Disease

KA Tarianyk, NV Lytvynenko, TY Purdenko… - 2022 - repository.pdmu.edu.ua
Levodopa is one of the most effective drugs for the treatment of Parkinson's disease.
However, the use of high doses of the drug has many adverse effects. Motor complications …

[图书][B] Endocannabinoid-Based Approaches towards Overcoming Opioid-Mediated Reward and Unwanted Side-Effects

V Iyer - 2021 - search.proquest.com
The non-medical use and abuse of prescription opioids have reached epidemic levels and
are a major public health problem globally. Opioids continue to be prescribed for chronic …