Sarco/endoplasmic reticulum calcium ATPase inhibitors: Beyond anticancer perspective

L Peterková, E Kmoníčková, T Ruml… - Journal of medicinal …, 2020 - ACS Publications
The sarco/endoplasmic reticulum calcium ATPase (SERCA), which plays a key role in the
maintenance of Ca2+ ion homeostasis, is an extensively studied enzyme, the inhibition of …

The [4+ 2] Cycloaddition of 2‐Pyrone in Total Synthesis.

Q Cai - Chinese Journal of Chemistry, 2019 - search.ebscohost.com
Diels‐Alder reaction is one of the most important reactions in organic synthesis and has
witnessed great achievements in total syntheses of complex natural products. In this review …

[HTML][HTML] Traditional medicinal knowledge of apiaceae at talassemtane national park (northern Morocco)

FZ Redouan, G Benítez, RM Picone, A Crisafulli… - South African Journal of …, 2020 - Elsevier
Abstract The Talassemtane National Park (PNTLS) represents a significant biome for flora
diversity in Morocco and North Africa. Based on its floristic richness and on the rural lifestyle …

Sesquiterpene lactones with unusual structure. Their biogenesis and biological activity

SM Adekenov - Fitoterapia, 2017 - Elsevier
The given review provides data on the new sesquiterpene lactones with unusual structure
isolated from various natural sources, eg fungi, plants, marine growth; about their spread …

The Claisen rearrangement in the syntheses of bioactive natural products

KC Majumdar, RK Nandi - Tetrahedron, 2013 - Elsevier
Since its discovery in 1912 by Ludwig Claisen 1 the Claisen rearrangement has stimulated
the interest of several generations of organic chemists and its importance is ever-increasing …

Resurrecting deadly carrots: towards a revision of Thapsia (Apiaceae) based on phylogenetic analysis of nrITS sequences and chemical profiles

C Weitzel, N Rønsted, K Spalik… - Botanical Journal of the …, 2014 - academic.oup.com
Thapsia is a small genus of herbaceous perennials in Apiaceae. Thapsia occurs around the
Mediterranean, extending from the Atlantic coasts of Portugal and Morocco to Crete and …

Generation of anti-trypanosomal agents through concise synthesis and structural diversification of sesquiterpene analogues

H Oguri, T Hiruma, Y Yamagishi… - Journal of the …, 2011 - ACS Publications
To access high-quality small-molecule libraries to screen lead candidates for neglected
diseases exemplified by human African trypanosomiasis, we sought to develop a synthetic …

A flavin-monooxygenase catalyzing oxepinone formation and the complete biosynthesis of vibralactone

KN Feng, Y Zhang, M Zhang, YL Yang, JK Liu… - Nature …, 2023 - nature.com
Oxepinone rings represent one of structurally unusual motifs of natural products and the
biosynthesis of oxepinones is not fully understood. 1, 5-Seco-vibralactone (3) features an …

Ionic Nucleophilic Catalysis of Chiral Ammonium Betaines for Highly Stereoselective Aldol Reaction from Oxindole-Derived Vinylic Carbonates

D Uraguchi, K Koshimoto, T Ooi - Journal of the American …, 2012 - ACS Publications
A new strategy for developing stereoselective bond-forming reactions is introduced; it takes
advantage of the ionic nucleophilic catalysis of chiral ammonium betaines to utilize vinylic …

Base-Catalyzed Diels−Alder Reactions of 2H-Pyran-2,5-diones: A Mild Approach to Basiliolide B

X Zhou, W Wu, X Liu, CS Lee - Organic Letters, 2008 - ACS Publications
A new class of base-catalyzed Diels− Alder reactions of 2 H-pyran-2, 5-diones has been
developed using catalytic amount of dicyclohexylmethylamine in tert-butyl alcohol. This …