Conspectus In nature, proteins range from those with highly ordered secondary and tertiary
structures to those that completely lack a well-defined three-dimensional structure, termed …

Introduction Polymer nanogels are among the most promising nanoplatforms for use in
biomedical applications. The substantial interest for these drug carriers is to enhance the …

Microstructured hydrogels are promising platforms to mimic structural and compositional
heterogeneities of the native extracellular matrix (ECM). The current state-of-the-art soft …

Peptide-based materials are diverse candidates for self-assembly into modularly designed
and stimuli-responsive nanostructures with precisely tunable compositions. Here, we …

Fusion of intrinsically disordered and globular proteins is a powerful strategy to create
functional nanomaterials. However, the immutable nature of genetic encoding restricts the …

Computationally designed homotetrameric helical peptide bundles have been
functionalized at their N-termini to achieve supramolecular polymers, wherein individual …

The unique biophysical and biochemical properties of intrinsically disordered proteins
(IDPs) and their recombinant derivatives, intrinsically disordered protein polymers (IDPPs) …

Proteins are incredibly complex materials. These sequence-defined polymers are capable of
assembling intro incredibly specific nanostructures through a complicated interplay of …

The hydrophobic interaction drives the association of non-polar molecules in water. It
governs the assembly of biomolecules, and plays a central role in biological phenomena …