An insight on medicinal attributes of 1, 2, 4-triazoles
R Aggarwal, G Sumran - European journal of medicinal chemistry, 2020 - Elsevier
The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …
Triazole hybrid compounds: A new frontier in malaria treatment
Reviewing the advancements in malaria treatment, the emergence of triazole hybrid
compounds stands out as a groundbreaking development. Combining the advantages of …
compounds stands out as a groundbreaking development. Combining the advantages of …
Pyridine- and Thiazole-Based Hydrazides with Promising Anti-inflammatory and Antimicrobial Activities along with Their In Silico Studies
V Kamat, R Santosh, B Poojary, SP Nayak… - ACS …, 2020 - ACS Publications
A new class of compounds formed by the linkage of− C (O)–NH–with pyridine and thiazole
moieties was designed, synthesized, and characterized by various spectral approaches. The …
moieties was designed, synthesized, and characterized by various spectral approaches. The …
Naproxen based 1, 3, 4-oxadiazole derivatives as EGFR inhibitors: Design, synthesis, anticancer, and computational studies
MM Alam, S Nazreen, ASA Almalki, AA Elhenawy… - Pharmaceuticals, 2021 - mdpi.com
A library of novel naproxen based 1, 3, 4-oxadiazole derivatives (8–16 and 19–26) has been
synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized …
synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized …
Design and synthesis of novel (S)-Naproxen hydrazide-hydrazones as potent VEGFR-2 inhibitors and their evaluation in vitro/in vivo breast cancer models
Naproxen is a common non-steroidal anti-inflammatory drug, which is the most usually used
propionic acid derivative for the treatment of many types of diseases. In this study, a series of …
propionic acid derivative for the treatment of many types of diseases. In this study, a series of …
1,3,4-Oxadiazole-naphthalene hybrids as potential VEGFR-2 inhibitors: design, synthesis, antiproliferative activity, apoptotic effect, and in silico studies
In the current work, some 1, 3, 4-oxadiazole-naphthalene hybrids were designed and
synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for …
synthesised as VEGFR-2 inhibitors. The synthesised compounds were evaluated in vitro for …
Coordination complexes built from a ditopic triazole-pyrazole ligand with antibacterial and antifungal performances
Four mononuclear complexes (H3O){[NiL3](ClO4) 3}(1),[CoL3](ClO4) 2· 2H2O
(2),[CdL2Cl2](3) and [CuL3](NO3) 2 (4) have been prepared employing a newly synthesized …
(2),[CdL2Cl2](3) and [CuL3](NO3) 2 (4) have been prepared employing a newly synthesized …
Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy
In search of small molecules for targeted therapy of non-small cell lung carcinoma (NSCLC),
an efficient four-step synthetic route was followed for the synthesis of new imidazothiazole …
an efficient four-step synthetic route was followed for the synthesis of new imidazothiazole …
Novel N-Acyl Hydrazone Compounds as Promising Anticancer Agents: Synthesis and Molecular Docking Studies
Y Biliz, B Hasdemir, H Başpınar Küçük… - ACS …, 2023 - ACS Publications
In this study, a new series of N-acyl hydrazones 7a-e, 8a-e, and 9a-e, starting from methyl δ-
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …
oxo pentanoate with different substituted groups 1a-e, were synthesized as anticancer …
[HTML][HTML] Ziziphus mauritiana Lam. Bark and Leaves: Extraction, Phytochemical Composition, In Vitro Bioassays and In Silico Studies
KI Sinan, S Dall'Acqua, S Sut, AI Uba, OK Etienne… - Plants, 2024 - mdpi.com
In this work, homogenizer-assisted extraction (HAE) and maceration (MAE) were applied on
leaves and bark of Ziziphus mauritiana using water and methanol (MeOH) as solvents. HAE …
leaves and bark of Ziziphus mauritiana using water and methanol (MeOH) as solvents. HAE …