Any spinal cord injury carries the potential for persistent disability affecting motor, sensory
and autonomic functions. To prevent this outcome, it is highly desirable to block a chain of …

OBJECTIVE Riluzole is a glutamatergic modulator that has recently shown potential for
neuroprotection after spinal cord injury (SCI). While the effects of riluzole are extensively …

Comorbidity exists between metabolic disorders and depressive syndrome with unclear
mechanisms. To characterize the causal relationship, we adopted a 12-week high-fat diet …

The nervous system was traditionally investigated by focusing primarily on neurons as main
functional units (“neurocentric” view)(1). Recently, this standpoint has changed, and glial …

Methylprednisolone sodium succinate (MPSS) has been proposed as a first-line treatment
for acute spinal cord injury (SCI). Its clinical use remains, however, controversial because of …

Although neuroprotection to contain the initial damage of spinal cord injury (SCI) is difficult,
multicentre studies show that early neurosurgery under general anaesthesia confers …

Study design: Retrospective case–control. Objectives: To characterize changes in American
Spinal Injury Association Motor Score (AMS) in patients treated with relative hypertension …

Activation of neuronal nicotinic acetylcholine receptors (nAChRs) by nicotine is reported to
protect brain neurons from glutamate excitotoxicity. We inquired whether a similar …

Neuroprotection of the spinal cord during the early phase of injury is an important goal to
determine a favorable outcome by prevention of delayed pathological events, including …

Microelectrode arrays (MEAs) represent an important tool to study the basic characteristics
of spinal networks that control locomotion in physiological conditions. Fundamental …