Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing

CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …

Insect hemocytes and their role in immunity

MD Lavine, MR Strand - Insect biochemistry and molecular biology, 2002 - Elsevier
The innate immune system of insects is divided into humoral and cellular defense
responses. Humoral defenses include antimicrobial peptides, the cascades that regulate …

An analysis of the structural and functional similarities of insect hemocytes and mammalian phagocytes

N Browne, M Heelan, K Kavanagh - Virulence, 2013 - Taylor & Francis
The insect immune response demonstrates a number of structural and functional similarities
to the innate immune system of mammals. As a result of these conserved features insects …

[HTML][HTML] Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

Invertebrate immunity: basic concepts and recent advances

NA Ratcliffe, AF Rowley, SW Fitzgerald… - International review of …, 1985 - Elsevier
Publisher Summary This chapter discusses basic concepts and advances of invertebrate
immunity. In mammals and other higher vertebrates, a plethora of information exists on the …

[HTML][HTML] The Virtuous Galleria mellonella Model for Scientific Experimentation

I Serrano, C Verdial, L Tavares, M Oliveira - Antibiotics, 2023 - mdpi.com
The first research on the insect Galleria mellonella was published 85 years ago, and the
larva is now widely used as a model to study infections caused by bacterial and fungal …

Insect haemocytes: what type of cell is that?

C Ribeiro, M Brehélin - Journal of insect physiology, 2006 - Elsevier
Classification of insect larvae circulating haemocytes is the subject of controversy, and the
terminology used to designate each cellular type is often different from one species to …

Entomogenous fungi

CW McCoy, RA Samson… - Handbook of natural …, 2019 - taylorfrancis.com
The fungi comprise a large, heterogeneous, and ubiquitous group of heterotrophic
organisms living as saprophytes or parasites, or associated with other organisms as …

[HTML][HTML] Immune Response of Galleria mellonella against Human Fungal Pathogens

N Trevijano-Contador, O Zaragoza - Journal of Fungi, 2018 - mdpi.com
In many aspects, the immune response against pathogens in insects is similar to the innate
immunity in mammals. This has caused a strong interest in the scientific community for the …

Granular cells are required for encapsulation of foreign targets by insect haemocytes

LL Pech, MR Strand - Journal of cell science, 1996 - journals.biologists.com
Haemocytes play an essential role in defending invertebrates against pathogens and
parasites that enter their haemocoel. A primary defense response is encapsulation; a …