Asprosin in health and disease, a new glucose sensor with central and peripheral metabolic effects

M Farrag, D Ait Eldjoudi… - Frontiers in …, 2023 - frontiersin.org
Adipose tissue malfunction leads to altered adipokine secretion which might consequently
contribute to an array of metabolic diseases spectrum including obesity, diabetes mellitus …

Can the new adipokine asprosin be a metabolic troublemaker for cardiovascular diseases? A state-of-the-art review

Z Zhang, L Zhu, Z Wang, N Hua, S Hu… - Progress in Lipid Research, 2023 - Elsevier
Adipokines play a significant role in cardiometabolic diseases. Asprosin, a newly discovered
adipokine, was first identified as a glucose-raising protein hormone. Asprosin also …

Fibrillin-1 and asprosin, novel players in metabolic syndrome

KM Summers, SJ Bush, MR Davis, DA Hume… - Molecular Genetics and …, 2023 - Elsevier
Fibrillin-1 is a major component of the extracellular microfibrils, where it interacts with other
extracellular matrix proteins to provide elasticity to connective tissues, and regulates the …

Serum asprosin correlates with indirect insulin resistance indices

M Mirr, A Braszak-Cymerman, A Ludziejewska… - Biomedicines, 2023 - mdpi.com
Background and Objectives: Insulin resistance is a major contributor to the development of
type 2 diabetes and can be assessed using indirect indicators calculated from non-invasive …

Asprosin levels in patients with type 2 diabetes mellitus, metabolic syndrome and obesity: A systematic review and meta-analysis

JR Ulloque-Badaracco, A Al-kassab-Córdova… - Diabetes & Metabolic …, 2024 - Elsevier
ABSTRACT Background & Aims Asprosin is a promising candidate for novel treatments for
metabolic–endocrine disorders. The objective of this systematic review and meta-analysis …

A cross-sectional comparative study on the effects of body mass index and exercise/sedentary on serum asprosin in male college students

R Huang, C Song, T Li, C Yu, T Yao, H Gao, S Cao… - Plos one, 2022 - journals.plos.org
Adipocytes regulate the body's metabolism by secreting adipokines to maintain energy
homeostasis. Asprosin is a new type of adipokine, and its relationship with obesity remains …

Asprosin: its function as a novel endocrine factor in metabolic-related diseases

Y Zhang, P Yang, X Zhang, S Liu, K Lou - Journal of Endocrinological …, 2024 - Springer
Background and purpose Asprosin was discovered as a new endocrine hormone originating
from fibrillin-1 cleavage that plays a crucial role in various metabolic-related diseases, such …

Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury

F Zheng, JZ Lei, JX Wang, XY Xu, B Zhou, R Ge… - Free Radical Biology …, 2025 - Elsevier
Ferroptosis is a type of non-apoptotic regulated cell death characterized by iron
accumulation and lipid peroxidation. Cisplatin is an effective chemotherapy drug with …

Association between serum asprosin and diabetic nephropathy in patients with type 2 diabetes mellitus in the community: A cross-sectional study

L Xu, J Cui, M Li, Q Wu, M Liu, M Xu, G Shi… - … and Obesity: Targets …, 2022 - Taylor & Francis
Objective To explore the association between serum asprosin and diabetic nephropathy
(DN) in patients with type 2 diabetes mellitus (T2DM) in the community. Methods In this cross …

Asprosin is positively associated with metabolic syndrome in hemodialysis patients: a cross-sectional study

J Zhou, W Yuan, Y Guo, Y Wang, Y Dai, Y Shen… - Renal Failure, 2023 - Taylor & Francis
Introduction Metabolic syndrome (MS) has a high prevalence in hemodialysis patients. High
asprosin levels are associated with the accumulation of adiposity and an increase in body …