Epidemiological and interventional human studies, as well as experiments in animal models, strongly indicate that helminth parasitic infections can confer protection from …
G Coakley, JL McCaskill, JG Borger, F Simbari… - Cell reports, 2017 - cell.com
Recent studies have demonstrated that many parasites release extracellular vesicles (EVs), yet little is known about the specific interactions of EVs with immune cells or their functions …
Heligmosomoides polygyrus is a natural intestinal parasite of mice, which offers an excellent model of the immunology of gastrointestinal helminth infections of humans and livestock. It is …
JP Hewitson, Y Harcus, J Murray, M van Agtmaal… - Journal of …, 2011 - Elsevier
The intestinal helminth parasite, Heligmosomoides polygyrus bakeri offers a tractable experimental model for human hookworm infections such as Ancylostoma duodenale and …
The nematode Heligmosomoides polygyrus is an excellent model for intestinal helminth parasitism. Infection in mice persists for varying lengths of time in different inbred strains …
CM Minutti, S Drube, N Blair, C Schwartz, JC McCrae… - Immunity, 2017 - cell.com
Gastro-intestinal helminth infections trigger the release of interleukin-33 (IL-33), which induces type-2 helper T cells (Th2 cells) at the site of infection to produce IL-13, thereby …
The intestinal nematode parasite Heligmosomoides polygyrus bakeri exerts widespread immunomodulatory effects on both the innate and adaptive immune system of the host …
CJC Johnston, E Robertson, Y Harcus… - JoVE (Journal of …, 2015 - jove.com
Heligmosomoides polygyrus (formerly known as Nematospiroides dubius, and also referred to by some as H. bakeri) is a gastrointestinal helminth that employs multiple …
HJ McSorley, MT O'Gorman, N Blair… - European journal of …, 2012 - Wiley Online Library
Allergic asthma is less prevalent in countries with parasitic helminth infections, and mice infected with parasites such as H eligmosomoides polygyrus are protected from allergic …