[HTML][HTML] The 2021 WHO classification of tumors of the thymus and mediastinum: what is new in thymic epithelial, germ cell, and mesenchymal tumors?

A Marx, JKC Chan, L Chalabreysse, S Dacic… - Journal of Thoracic …, 2022 - Elsevier
This overview of the fifth edition of the WHO classification of thymic epithelial tumors
(including thymomas, thymic carcinomas, and thymic neuroendocrine tumors [NETs]) …

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

T Fujisawa, P Filippakopoulos - Nature reviews Molecular cell biology, 2017 - nature.com
Bromodomains (BRDs) are evolutionarily conserved protein–protein interaction modules
that are found in a wide range of proteins with diverse catalytic and scaffolding functions and …

The integrated genomic landscape of thymic epithelial tumors

M Radovich, CR Pickering, I Felau, G Ha, H Zhang… - Cancer cell, 2018 - cell.com
Thymic epithelial tumors (TETs) are one of the rarest adult malignancies. Among TETs,
thymoma is the most predominant, characterized by a unique association with autoimmune …

Pembrolizumab in patients with thymic carcinoma: a single-arm, single-centre, phase 2 study

G Giaccone, C Kim, J Thompson, C McGuire… - The Lancet …, 2018 - thelancet.com
Background Treatment options are limited for patients with thymic carcinoma. These
aggressive tumours are not typically associated with paraneoplastic autoimmune disorders …

Lenvatinib in patients with advanced or metastatic thymic carcinoma (REMORA): a multicentre, phase 2 trial

J Sato, M Satouchi, S Itoh, Y Okuma, S Niho… - The Lancet …, 2020 - thelancet.com
Background Thymic carcinoma is a rare malignant disease and standard treatment for
advanced or metastatic thymic carcinoma previously treated with platinum-based …

Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell–derived lymphomas

D Vallois, MPD Dobay, RD Morin… - Blood, The Journal …, 2016 - ashpublications.org
Angioimmunoblastic T-cell lymphoma (AITL) and other lymphomas derived from follicular T-
helper cells (TFH) represent a large proportion of peripheral T-cell lymphomas (PTCLs) with …

Sunitinib in patients with chemotherapy-refractory thymoma and thymic carcinoma: an open-label phase 2 trial

A Thomas, A Rajan, A Berman, Y Tomita… - The Lancet …, 2015 - thelancet.com
Background No standard treatments are available for advanced thymic epithelial tumours
after failure of platinum-based chemotherapy. We investigated the activity of sunitinib, an …

[HTML][HTML] The 2015 World Health Organization classification of tumors of the thymus: continuity and changes

A Marx, JKC Chan, JM Coindre, F Detterbeck… - Journal of Thoracic …, 2015 - Elsevier
This overview of the 4th edition of the World Health Organization (WHO) Classification of
thymic tumors has two aims. First, to comprehensively list the established and new tumor …

[HTML][HTML] Single-arm, multicentre, phase II trial of nivolumab for unresectable or recurrent thymic carcinoma: PRIMER study

Y Katsuya, H Horinouchi, T Seto, S Umemura… - European Journal of …, 2019 - Elsevier
Introduction Thymic carcinoma (TC) is a rare cancer with a poor prognosis and limited
treatment options, especially after relapse. Methods In this open-label, two-stage …

Phase II study of everolimus in patients with thymoma and thymic carcinoma previously treated with cisplatin-based chemotherapy

PA Zucali, T De Pas, G Palmieri, A Favaretto… - Journal of Clinical …, 2018 - ascopubs.org
Purpose No effective salvage treatments are available for patients with advanced/recurrent
thymoma (T) or thymic carcinoma (TC) who have progressed after platinum-based …