Modulation of gene expression rather than monoamine oxidase inhibition: (-)-Deprenyl-related compounds in controlling neurodegeneration

WG Tatton - Neurology, 1996 - AAN Enterprises
(-)-Deprenyl has been used to irreversibly inhibit monoamine oxidase B (MAO-B) in
Parkinson's disease (PD) and Alzheimer's disease (AD) as a possible means of improving …

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

N Zamzami, P Marchetti, M Castedo… - The Journal of …, 1995 - rupress.org
Programmed cell death (PCD) is a physiological process commonly defined by alterations in
nuclear morphology (apoptosis) and/or characteristic stepwise degradation of chromosomal …

Normal and abnormal consequences of apoptosis in the human heart

TN James - Annual review of physiology, 1998 - annualreviews.org
▪ Abstract Knowledge about apoptosis has become essential for understanding many
aspects of cardiac structure and function. In the human heart there are major periods of …

Therapeutic preparations of normal polyspecific IgG (IVIg) induce apoptosis in human lymphocytes and monocytes: a novel mechanism of action of IVIg involving the …

NKA Prasad, G Papoff, A Zeuner, E Bonnin… - The Journal of …, 1998 - journals.aai.org
Therapeutic preparations of normal human IgG for iv use (IVIg) exhibit a broad spectrum of
immunoregulatory activities in vitro and in vivo. IVIg has been shown to inhibit the …

Splenic B lymphocyte programmed cell death is prevented by nitric oxide release through mechanisms involving sustained Bcl-2 levels.

AM Genaro, S Hortelano, A Alvarez… - The Journal of …, 1995 - Am Soc Clin Investig
Incubation of ex vivo cultured mature B cells in the presence of nitric oxide or nitric oxide-
donor substances delays programmed cell death as determined by the appearance of DNA …

Внутриклеточный окислительный стресс и апоптоз

НК Зенков, ЕБ Менщикова, НН Вольский… - Успехи современной …, 1999 - elibrary.ru
Проведен анализ особенностей развития окислительного стресса при индукции
запрограммированной гибели клеток–апоптоза. Показано, что цитокины, стероидные …

Catalase contents in cells determine sensitivity to the apoptosis inducer gallic acid

K Isuzugawa, M Inoue, Y Ogihara - Biological and Pharmaceutical …, 2001 - jstage.jst.go.jp
Catalase Contents in Cells Determine Sensitivity to the Apoptosis Inducer Gallic Acid Page 1
Apoptosis is biological cell death for normal tissue homeostasis, cellular differentiation, and …

Mechanisms of nerve cell death: apoptosis or necrosis after cerebral ischaemia

RME Chalmers-Redman, AD Fraser, WYH Ju… - International review of …, 1996 - Elsevier
Publisher Summary Nerve cell death in human stroke was believed to be necrotic. In the
1970s and early 1980s, evidence of a different form of cell death termed “apoptosis” was …

Invited review: cell volume control and signal transduction in apoptosis

M Gómez-Angelats, JA Cidlowski - Toxicologic pathology, 2002 - journals.sagepub.com
Apoptosis is a physiological form of death in which cells turn-on an intrinsic genetic program
that eventually leads to their destruction in a highly regulated manner. This process renders …

Signaling in unicellular eukaryotes

ST Christensen, V Leick, L Rasmussen… - International Review of …, 1997 - Elsevier
Aspects of intercellular and intracellular signaling systems in cell survival, proliferation,
differentiation, chemosensory behavior, and programmed cell death in free-living unicellular …