Preeclampsia is a pregnancy-specific disorder, of which one of its major subtypes, the
placental subtype is considered a response to an ischemic placental environment, impacting …

Preeclampsia (PE) is a multisystem heterogeneous complication of pregnancy remaining a
leading cause of maternal and perinatal morbidity and mortality over the world. PE has a …

Systemic manifestation of preeclampsia (PE) is associated with circulating factors, including
inflammatory cytokines and damage-associated molecular patterns (DAMPs), or alarmins …

Importance A genetic contribution to preeclampsia susceptibility has been established but is
still incompletely understood. Objective To disentangle the underlying genetic architecture of …

Preeclampsia (PE) is the leading cause of maternal and fetal mortality globally and may
trigger dementia later in life in mothers and their offspring. However, the etiological drivers …

The etiology of preeclampsia (PE), a serious pregnancy complication, remains an enigma.
We have demonstrated that proteinopathy, a pathologic feature of neurodegenerative …

Transthyretin (TTR), an homotetrameric protein mainly synthesized by the liver and the
choroid plexus, and secreted into the blood and the cerebrospinal fluid, respectively, has …

Protein misfolding underlies the pathology of a large number of human disorders, many of
which are age-related. An exception to this is preeclampsia, a leading cause of pregnancy …

Pre‐eclampsia is a hypertensive disease of pregnancy characterized by new‐onset
hypertension, with either proteinuria and/or organ dysfunction. Pre‐eclampsia is a leading …

Understanding of sterile inflammation and its associated biological triggers and diseases is
still at the elementary stage. This becomes more warranted in cases where infections are not …