Emerging evidence indicates that heat shock proteins (HSPs) are critical regulators in
normal neural physiological function as well as in cell stress responses. The functions of …

The family of the human small Heat Shock Proteins (HSPBs) consists of ten members of
chaperones (HSPB1-HSPB10), characterized by a low molecular weight and capable of …

Alzheimer disease is a neurological disorder that is characterized by the presence of fibrils
and oligomers composed of the amyloid β (Aβ) peptide. In models of Alzheimer disease …

Alzheimer's disease is a progressive neurodegenerative disorder characterised by the
gradual onset of dementia. The pathological hallmarks of the disease are β‐amyloid (Aβ) …

The molecular chaperone HspB8 [Hsp (heat-shock protein) B8] is member of the B-group of
Hsps. These proteins bind to unfolded or misfolded proteins and protect them from …

Aberrant protein aggregation is a defining feature of most neurodegenerative diseases.
During pathological aggregation, key proteins transition from their native state to alternative …

Abstract αB-Crystallin is a small heat-shock protein (sHsp) that is colocalized with α-
synuclein (αSyn) in Lewy bodies—the pathological hallmarks of Parkinson's disease—and …

Expression of the human β-amyloid peptide (Aβ) in a transgenic Caenorhabditis elegans
Alzheimer disease model leads to the induction of HSP-16 proteins, a family of small heat …

Alzheimer's disease (AD), the most common neurodegenerative disorder in the aged, is
characterized by the cerebral deposition of fibrils formed by the amyloid β-protein (Aβ), a 40 …

Neurodegenerative diseases involve the progressive deterioration of structures within the
central nervous system responsible for motor control, cognition, and autonomic function …