Objective: High prevalence of diabetes mellitus (DM) along with the poor health outcomes
and the escalated costs of treatment and care poses the need to focus on prevention, early …

Blood glucose control algorithms have evolved since the beginnings of the artificial
pancreas in diabetes treatment. Although the main problem to solve remains as the …

This paper aims at the development and evaluation of a personalized insulin infusion
advisory system (IIAS), able to provide real-time estimations of the appropriate insulin …

Automated control of blood glucose in patients with type-1 diabetes has not yet been fully
implemented. The aim of this study was to design and clinically evaluate a system that …

With the aim of regulating plasma glucose level in a type-1 diabetic patient, a nonlinear
explicit model predictive control (NEMPC) is developed. The computational complexity in …

Artificial pancreas (AP) systems perform automated insulin delivery to subjects with type 1
diabetes mellitus (T1DM). In this paper, a nonlinear suboptimal controller is designed to …

Type 1 diabetic patients need insulin therapy to keep their blood glucose close to normal. In
this paper an attempt is made to show how nonlinear control-oriented model may be used to …

Physiological variations in people with type 1 diabetes constantly change the insulin
requirements of patients which, if not compensated, can lead to insulin overdose or insulin …

Patients with type 1 diabetes require insulin therapy to maintain blood glucose levels within
safe ranges since their pancreas is unable to complete its function. The development of a …

Background: Clinical studies have shown that the Medtronic proportional-integral-derivative
(PID) control with insulin feedback (IFB) provides stable 24 h glucose control, but with high …