Molecular imaging

R Weissleder, U Mahmood - Radiology, 2001 - pubs.rsna.org
The term molecular imaging can be broadly defined as the in vivo characterization and
measurement of biologic processes at the cellular and molecular level. In contradistinction to …

Applications for preclinical PET/MRI

MS Judenhofer, SR Cherry - Seminars in nuclear medicine, 2013 - Elsevier
Currently, the combination of positron emission tomography (PET) and magnetic resonance
imaging (MRI) as a hybrid imaging modality is receiving great attention not only in its …

Progressive hypertrophy and heart failure in β1-adrenergic receptor transgenic mice

S Engelhardt, L Hein, F Wiesmann… - Proceedings of the …, 1999 - National Acad Sciences
Stimulation of cardiac β1-adrenergic receptors is the main mechanism that increases heart
rate and contractility. Consequently, several pharmacological and gene transfer strategies …

[HTML][HTML] Effects of isoflurane anesthesia on the cardiovascular function of the C57BL/6 mouse

C Constantinides, R Mean… - ILAR journal/National …, 2011 - ncbi.nlm.nih.gov
Isoflurane (ISO) is the most commonly used inhalational anesthetic for experimental
interventions in mice and is preferred for imaging technologies that require the mouse to …

Sparseness prior based iterative image reconstruction for retrospectively gated cardiac micro‐CT

J Song, QH Liu, GA Johnson, CT Badea - Medical physics, 2007 - Wiley Online Library
Recent advances in murine cardiac studies with three‐dimensional (3D) cone beam micro‐
CT used a retrospective gating technique. However, this sampling technique results in a …

Cooperative control of striated muscle mass and metabolism by MuRF1 and MuRF2

CC Witt, SH Witt, S Lerche, D Labeit, W Back… - The EMBO …, 2008 - embopress.org
The muscle‐specific RING finger proteins MuRF1 and MuRF2 have been proposed to
regulate protein degradation and gene expression in muscle tissues. We have tested the in …

Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction

M Nahrendorf, K Hu, S Frantz, FA Jaffer, CH Tung… - Circulation, 2006 - Am Heart Assoc
Background—Identification of key molecular players in myocardial healing could lead to
improved therapies, reduction of scar formation, and heart failure after myocardial infarction …

Use of echocardiography for the phenotypic assessment of genetically altered mice

KA Collins, CE Korcarz, RM Lang - Physiological genomics, 2003 - journals.physiology.org
Transgenic mice displaying abnormalities in cardiac development and function represent a
powerful new tool for understanding molecular mechanisms underlying normal …

Developmental changes of cardiac function and mass assessed with MRI in neonatal, juvenile, and adult mice

F Wiesmann, J Ruff, KH Hiller… - American Journal …, 2000 - journals.physiology.org
Cardiovascular transgenic mouse models with an early phenotype or even premature death
require noninvasive imaging methods that allow for accurate visualization of cardiac …

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets

A Bogdanov Jr, L Matuszewski, C Bremer… - Molecular …, 2002 - journals.sagepub.com
Magnetic resonance imaging (MRI) has evolved into a sophisticated, noninvasive imaging
modality capable of high-resolution anatomical and functional characterization of transgenic …