Neurofibromatosis (NF) and schwannomatosis (SWN) are genetic conditions characterized
by the risk of developing nervous system tumors. Recently revised diagnostic criteria include …

Breast cancer remains a significant contributor to morbidity and mortality within oncology.
Risk factors, encompassing genetic and environmental influences, significantly contribute to …

Introduction Female-specific cancers seriously affect physical and psychological health of
women worldwide. Objectives We aimed to elucidate trends in the age-standardized …

Common variants of genes involved in DNA damage correction [tumor protein p53 (TP53),
murine double 2 homolog oncoprotein (MDM2) and ataxia‑telengiectasia mutated (ATM)] …

Goals To determine whether an 18 single nucleotide polymorphisms (SNPs) polygenic risk
score (PRS18) improves breast cancer (BC) risk prediction for women at above-average risk …

Breast cancer is the most prominent type of cancer among females and treatment through
chemotherapy generates serious side effects too along with the cure. Hence, the use of …

Simple Summary Around 50% of the familial breast cancer (BC) cases are estimated to be
caused by variants in low-, moderate-, and high-risk susceptibility genes; however, the other …

Approximately 20% of breast cancer cases are attributed to increased family risk, yet
variation in BRCA1/2 can only explain 20%–25% of cases. Historically, only single gene or …

Background Genes exist in a population in a variety of forms (alleles), as a consequence of
multiple mutation events that have arisen over the course of time. In this work we consider a …

Female breast cancer is the most common and the fifth deadliest cancer worldwide. It is
influenced by a combination of genetic, hormonal, and environmental factors. The excision …