This Review examines recent developments in late transition metal-catalyzed
hydroamination and-amidation reactions. A hydroamination is a reaction in which an N− H …

With their mechanistic novelty and various modalities of reactivity, transition metal
unsaturated carbene (alkenylidene) complexes have emerged as versatile intermediates for …

Chiral alkyl amines are omnipresent as bioactive molecules and synthetic intermediates.
The catalytic and enantioselective synthesis of alkyl amines from readily accessible …

Reported herein is the development of the Ir (III)-catalyzed direct C–H amidation of arenes
and alkenes using acyl azides as the nitrogen source. This procedure utilizes an in situ …

The formal hydroamination/hydroamidation utilizing metal hydride is an appealing synthetic
tool for the construction of valuable nitrogen-containing compounds from unsaturated …

Sweet cyclizations: The synthesis of pyrrolizidines and indolizidines has been achieved.
Olefins were subjected to an intramolecular palladium-catalyzed aminoalkynylation with the …

The selective construction of carbon–fluorine bonds is of great interest to medicinal chemists
because the replacement of a carbon–hydrogen bond with a carbon–fluorine bond …

The additions of various nucleophiles (XeH) to carbonecarbon (CeC) multiple bonds are of
prime importance in synthetic organic chemistry. These essentially simple reactions allow …

Olefin aminations are important synthetic technologies for the construction of aliphatic C–N
bonds. Here we report a catalytic protocol for olefin hydroamidation that proceeds through …

Amide bond-forming reactions are of tremendous significance in synthetic chemistry.
Methodological research has, in the past, focused on efficiency and selectivity, and these …