MPAD: A Database for Binding Affinity of Membrane Protein–protein Complexes and their Mutants

F Ridha, A Kulandaisamy, MM Gromiha - Journal of Molecular Biology, 2023 - Elsevier
Membrane protein complexes are crucial for a large variety of biological functions which are
mainly dictated by their binding affinity. Due to the intricate nature of their structure, however …

PCA-MutPred: prediction of binding free energy change upon missense mutation in protein-carbohydrate complexes

NRS Shanmugam, K Veluraja, MM Gromiha - Journal of Molecular Biology, 2022 - Elsevier
Protein-carbohydrate interactions play an important role in several biological processes. The
mutation of amino acid residues in carbohydrate-binding proteins may alter the binding …

Binding affinity changes upon mutation in protein–protein complexes

R Nikam, F Ridha, S Jemimah… - PROTEIN …, 2025 - World Scientific
Protein–protein interactions (PPIs) are central to the functioning of living organisms,
orchestrating various biological processes. Intermolecular forces and binding interfaces …