African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping

MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

[HTML][HTML] The evolution of human genetic and phenotypic variation in Africa

MC Campbell, SA Tishkoff - Current biology, 2010 - cell.com
Africa is the birthplace of modern humans, and is the source of the geographic expansion of
ancestral populations into other regions of the world. Indigenous Africans are characterized …

Inferring human population size and separation history from multiple genome sequences

S Schiffels, R Durbin - Nature genetics, 2014 - nature.com
The availability of complete human genome sequences from populations across the world
has given rise to new population genetic inference methods that explicitly model ancestral …

[HTML][HTML] Inferring the joint demographic history of multiple populations from multidimensional SNP frequency data

RN Gutenkunst, RD Hernandez, SH Williamson… - PLoS …, 2009 - journals.plos.org
Demographic models built from genetic data play important roles in illuminating prehistorical
events and serving as null models in genome scans for selection. We introduce an inference …

Bayesian inference of ancient human demography from individual genome sequences

I Gronau, MJ Hubisz, B Gulko, CG Danko, A Siepel - Nature genetics, 2011 - nature.com
Whole-genome sequences provide a rich source of information about human evolution.
Here we describe an effort to estimate key evolutionary parameters based on the whole …

Demographic history and rare allele sharing among human populations

S Gravel, BM Henn, RN Gutenkunst… - Proceedings of the …, 2011 - National Acad Sciences
High-throughput sequencing technology enables population-level surveys of human
genomic variation. Here, we examine the joint allele frequency distributions across …

Species delimitation with gene flow

ND Jackson, BC Carstens, AE Morales… - Systematic …, 2017 - academic.oup.com
Species are commonly thought to be evolutionarily independent in a way that populations
within a species are not. In recent years, studies that seek to identify evolutionarily …

Genome-wide patterns of population structure and admixture in West Africans and African Americans

K Bryc, A Auton, MR Nelson… - Proceedings of the …, 2010 - National Acad Sciences
Quantifying patterns of population structure in Africans and African Americans illuminates
the history of human populations and is critical for undertaking medical genomic studies on …

[HTML][HTML] Length distributions of identity by descent reveal fine-scale demographic history

PF Palamara, T Lencz, A Darvasi, I Pe'er - The American journal of human …, 2012 - cell.com
Data-driven studies of identity by descent (IBD) were recently enabled by high-resolution
genomic data from large cohorts and scalable algorithms for IBD detection. Yet, haplotype …

The environmental context for the origins of modern human diversity: a synthesis of regional variability in African climate 150,000–30,000 years ago

MW Blome, AS Cohen, CA Tryon, AS Brooks… - Journal of human …, 2012 - Elsevier
We synthesize African paleoclimate from 150 to 30 ka (thousand years ago) using 85
diverse datasets at a regional scale, testing for coherence with North Atlantic …