A comprehensive review on solitary fibrous tumor: new insights for new horizons

J Martin-Broto, JL Mondaza-Hernandez, DS Moura… - Cancers, 2021 - mdpi.com
Simple Summary Solitary fibrous tumor (SFT) is a malignant condition that exhibits different
clinical behaviors ranging from low to high aggressive SFT, with dedifferentiated SFT (DD …

Improving immunotherapy efficacy in soft-tissue sarcomas: A biomarker driven and histotype tailored review

M Roulleaux Dugage, EF Nassif, A Italiano… - Frontiers in …, 2021 - frontiersin.org
Anti-PD-(L) 1 therapies yield a disappointing response rate of 15% across soft-tissue
sarcomas, even if some subtypes benefit more than others. The proportions of TAMs and …

[HTML][HTML] Soft tissue and visceral sarcomas: ESMO–EURACAN–GENTURIS Clinical Practice Guidelines for diagnosis, treatment and follow-up☆

A Gronchi, AB Miah, AP Dei Tos, N Abecassis… - Annals of …, 2021 - Elsevier
Highlights•This Clinical Practice Guideline provides key recommendations on the
management of soft tissue and visceral sarcomas.•Recommendations have been agreed …

Novel therapeutic options for solitary fibrous tumor: antiangiogenic therapy and beyond

A de Bernardi, A Dufresne, F Mishellany, JY Blay… - Cancers, 2022 - mdpi.com
Simple Summary In the latest WHO classification, solitary fibrous tumors (SFTs) are now
subdivided into benign SFT (intermediate category (locally aggressive)), SFT NOS …

Pazopanib in advanced soft tissue sarcomas

ATJ Lee, RL Jones, PH Huang - Signal transduction and targeted …, 2019 - nature.com
Pazopanib is the first and only tyrosine kinase inhibitor currently approved for the treatment
of multiple histological subtypes of soft tissue sarcoma (STS). Initially developed as a small …

Pazopanib for treatment of typical solitary fibrous tumours: a multicentre, single-arm, phase 2 trial

J Martin-Broto, J Cruz, N Penel, A Le Cesne… - The Lancet …, 2020 - thelancet.com
Background Solitary fibrous tumour is an ultra-rare sarcoma, which encompasses different
clinicopathological subgroups. The dedifferentiated subgroup shows an aggressive course …

[HTML][HTML] Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour

T Georgiesh, HM Namløs, N Sharma, S Lorenz… - Pathology, 2021 - Elsevier
Solitary fibrous tumour (SFT) is a mesenchymal neoplasm characterised by pathognomonic
NAB2-STAT6 gene fusions. The clinical implications and prognostic value of different fusion …

Toward better understanding and management of solitary fibrous tumor

K Kazazian, EG Demicco, M de Perrot… - Surgical Oncology …, 2022 - surgonc.theclinics.com
Surg Oncol Clin N Am 31 (2022) 459–483 https://doi. org/10.1016/j. soc. 2022.03. 009
surgonc. theclinics. com 1055-3207/22/© 2022 Elsevier Inc. All rights reserved …

Comprehensive analysis reveals potential therapeutic targets and an integrated risk stratification model for solitary fibrous tumors

R Zhang, Y Yang, C Hu, M Huang, W Cen… - Nature …, 2023 - nature.com
Solitary fibrous tumors (SFTs) are rare mesenchymal tumors with unpredictable evolution
and with a recurrence or metastasis rate of 10-40%. Current medical treatments for relapsed …

Pazopanib for treatment of advanced extraskeletal myxoid chondrosarcoma: a multicentre, single-arm, phase 2 trial

S Stacchiotti, S Ferrari, A Redondo, N Hindi… - The Lancet …, 2019 - thelancet.com
Background Extraskeletal myxoid chondrosarcoma is a rare sarcoma with low sensitivity to
cytotoxic chemotherapy. Retrospective evidence suggests that antiangiogenic drugs could …