A systematic review and meta-analysis on multiple cytokine gene polymorphisms in the pathogenesis of periodontitis

X Liu, H Li - Frontiers in immunology, 2022 - frontiersin.org
Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

TNF‐α gene promoter polymorphisms contribute to periodontitis susceptibility: evidence from 46 studies

C Ding, X Ji, X Chen, Y Xu… - Journal of Clinical …, 2014 - Wiley Online Library
Aim Tumour necrosis factor‐alpha (TNF‐α) plays a critical role in the pathogenesis of
periodontal disease. TNF‐α gene polymorphisms can influence the TNF‐α production. Many …

Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview

Z Heidari, B Moudi, H Mahmoudzadeh-Sagheb - BMC Oral Health, 2019 - Springer
Background Chronic periodontitis (CP), defines as destruction of the supporting tissues of
the teeth and resorption of the alveolar bone. It is widespread in human populations and …

Association between tumor necrosis factor-α promoter− 308 A/G,− 238 A/G, interleukin-6− 174 G/C and− 572 G/C polymorphisms and periodontal disease: a meta …

GG Song, SJ Choi, JD Ji, YH Lee - Molecular biology reports, 2013 - Springer
The aim of this study was to determine whether tumor necrosis factor-α (TNF-α) and
interleukin-6 (IL-6) promoter polymorphisms confer susceptibility to periodontitis in ethnically …

Interleukin gene variability and periodontal bacteria in patients with generalized aggressive form of periodontitis

P Borilova Linhartova, Z Danek, T Deissova… - International journal of …, 2020 - mdpi.com
Host genetic predispositions to dysregulated immune response can influence the
development of the aggressive form of periodontitis (AgP) through susceptibility to oral …

Association of the IL-10 polymorphisms and periodontitis: a meta-analysis

CM Albuquerque, AJ Cortinhas, FJ Morinha… - Molecular Biology …, 2012 - Springer
No clear consensus has been reached regarding the association of IL-10 polymorphisms
and periodontitis. Therefore, we performed a meta-analysis of case–control studies and a …

Impact of host gene polymorphisms on susceptibility to chronic hepatitis B virus infection

B Moudi, Z Heidari… - Infection, Genetics and …, 2016 - Elsevier
Hepatitis B virus (HBV) infection can result in a number of different clinical conditions,
including asymptomatic HBV carriers to chronic hepatitis and primary hepatocellular …

Variations in inflammatory genes are associated with periodontitis

M Ianni, G Bruzzesi, D Pugliese, E Porcellini… - Immunity & …, 2013 - Springer
Background Periodontitis is a multi-factorial disease and several risk-factors such as
infections, inflammatory responses, oral hygiene, smoke, aging and individual …

IL-6 and IL-10 gene polymorphisms in patients with aggressive periodontitis: effects on GCF, serum and clinic parameters

E PIRIM GORGUN, H Toker, EM Korkmaz… - Brazilian oral …, 2017 - SciELO Brasil
Genetic variations observed in cytokines affect periodontitis susceptibility. The aim of this
study was to investigate interleukin (IL)-6 (-174) and IL-10 (-597) gene polymorphisms in …

Association between tumor necrosis factor-α (G-308A) polymorphism and chronic periodontitis, aggressive periodontitis, and peri-implantitis: a meta-analysis

X Zhang, X Zhu, W Sun - Journal of Evidence Based Dental Practice, 2021 - Elsevier
Objective Chronic periodontitis (CP), aggressive periodontitis (AP), and peri-implantitis (PI)
are chronic inflammatory diseases. Tumor necrosis factor-α (TNF-a) is an effective immune …