Occult hepatitis B infection and hepatocellular carcinoma: Epidemiology, virology, hepatocarcinogenesis and clinical significance

LY Mak, DKH Wong, T Pollicino, G Raimondo… - Journal of …, 2020 - Elsevier
Occult hepatitis B infection (OBI) refers to a condition where replication-competent HBV DNA
is present in the liver, with or without HBV DNA in the blood, in individuals with serum …

Occult hepatitis B virus infection: an update

C Saitta, T Pollicino, G Raimondo - Viruses, 2022 - mdpi.com
Occult hepatitis B virus (HBV) infection (OBI) refers to a condition in which replication-
competent viral DNA is present in the liver (with detectable or undetectable HBV DNA in the …

Tumor mutational burden for predicting prognosis and therapy outcome of hepatocellular carcinoma

D Gabbia, S De Martin - International journal of molecular sciences, 2023 - mdpi.com
Hepatocellular carcinoma (HCC), the primary hepatic malignancy, represents the second-
highest cause of cancer-related death worldwide. Many efforts have been devoted to finding …

Insights into hepatitis B virus DNA integration-55 years after virus discovery

K Zhao, A Liu, Y Xia - The Innovation, 2020 - cell.com
Hepatitis B virus (HBV), which was discovered in 1965, is a threat to global public health.
HBV infects human hepatocytes and leads to acute and chronic liver diseases, and there is …

Detection technology and clinical applications of serum viral products of hepatitis B virus infection

Y Liu, D Wu, K Zhang, R Ren, Y Liu, S Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Viral hepatitis, caused by its etiology, hepatitis virus, is a public health problem globally.
Among all infections caused by hepatitis-associated viruses, hepatitis B virus (HBV) infection …

[HTML][HTML] The correlation and role analysis of COL4A1 and COL4A2 in hepatocarcinogenesis

Y Liu, J Zhang, Y Chen, H Sohel, X Ke, J Chen… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Liver fibrosis biomarker, Type IV collagen, may function as hepatocarcinogenesis niche.
However, among the six isoforms, the isoforms providing tumor microenvironment and their …

Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus …

R Salpini, S D'Anna, L Benedetti, L Piermatteo… - Frontiers in …, 2022 - frontiersin.org
Chronic infection with Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and
mortality worldwide. HBV-DNA integration into the human genome is recognized as a …

Single-cell sequencing and its applications in liver cancer

B Tian, Q Li - Frontiers in Oncology, 2022 - frontiersin.org
As one of the most lethal cancers, primary liver cancer (PLC) has high tumor heterogeneity,
including the heterogeneity between cancer cells. Traditional methods which have been …

Prevalence of Hepatocellular Carcinoma in Hepatitis B Population within Southeast Asia: A Systematic Review and Meta-Analysis of 39,050 Participants

AA Rabaan, KE Bello, AA Irekeola, NAA Kaabi… - Pathogens, 2023 - mdpi.com
Background and aim: Hepatocellular carcinoma (HCC) is a significant complication of
hepatitis B and still poses a global public health concern. This systematic review and meta …

HBV infection in HIV-driven immune suppression

L Sarmati, V Malagnino - Viruses, 2019 - mdpi.com
Worldwide, approximately 10% of all human immunodeficiency virus (HIV)-infected people
are also chronically coinfected with hepatitis B virus (HBV). HBV infection has a poor …