Trypanosoma cruzi interacts with the different arms of the innate and adaptive host's immune
response in a very complex and flowery manner. The history of host-parasite co-evolution …

CD8+ T cells are crucial to the control of Trypanosoma cruzi infection and probably act via
multiple mechanisms, the most important being the production of interferon‐γ (IFN‐γ). In the …

The present study evaluated the immunogenicity of new malaria vaccine formulations based
on the 19kDa C-terminal fragment of Plasmodium vivax Merozoite Surface Protein-1 …

Infection with Trypanosoma cruzi results in the development of both type 1 and type 2
patterns of cytokine responses during acute and chronic stages of infection. To investigate …

The mechanisms involved in the pathology of chronic chagasic cardiomyopathy are still
debated, and the controversy has interfered with the development of new treatments and …

Immunity to Trypanosoma cruzi requires elicitation of humoral and cell-mediated immune
responses to extracellular trypomastigotes and intracellular amastigotes. In this study, the …

Chagas disease is caused by the flagellate protozoan Trypanosoma cruzi, affecting millions
of people throughout Latin America. The parasite dampens host immune response causing …

The Trypanosoma cruzi trans-sialidase (TS) is a unique enzyme with neuraminidase and
sialic acid transfer activities important for parasite infectivity. The T. cruzi genome contains a …

T rypanosoma cruzi trans‐sialidase (TS) was identified three decades ago. TS catalyses a
trans‐glycosylation reaction, transferring SA from sialylated donors to the terminal galactose …

The kinetics of effector CD8+-T-cell responses to specific Trypanosoma cruzi epitopes was
investigated after challenge. Our results suggest that the delayed kinetics differs from that …