Conspectus Carbon dioxide (CO2) is recognized as a greenhouse gas and a common
waste product. Simultaneously, it serves as an advantageous and commercially available …

Utilizing electrons directly offers significant potential for advancing organic synthesis by
facilitating novel reactivity and enhancing selectivity under mild conditions. As a result, an …

Here we present the discovery and development of a highly selective aromatic C–H
amination reaction. This electrochemical strategy involves a cathodic reduction process that …

Two general protocols for the regioselective electrochemically enabled sulfonylation
cyclization of N-alkenylacrylamides with sodium sulfinates or sulfonyl hydrazides were …

Efficient and streamlined synthetic methods that facilitate the rapid build-up of structurally
diverse π-conjugated systems are of paramount importance in the quest for organic …

Incorporation of C (sp3)–F bonds in biologically active compounds is a common strategy
employed in medicinal and agricultural chemistry to tune pharmacokinetic and …

Glycosyl donor activation emerged as an enabling technology for anomeric
functionalization, but aimed primarily at O-glycosylation. In contrast, we herein disclose …

Sulfur (VI) fluoride exchange (SuFEx) is a second-generation click chemistry reaction that
relies on the unique reactivities of SVI–F bonds. The development of efficient methods for …

Catalytic C–H borylation is of prime topical importance, since easily available feedstock
chemicals can thereby be transformed into valuable transient functional groups in the …

The reductive activation of chemical bonds at less negative potentials provides a foundation
for high functional group tolerance and selectivity, and it is one of the central topics in …