• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Cardiovascular defects, injuries, and degenerative diseases often require surgical
intervention and the use of implantable replacement material and conduits. Traditional …

Importance The role of ticagrelor with or without aspirin after coronary artery bypass graft
surgery remains unclear. Objective To compare the risks of vein graft failure and bleeding …

Objective To assess the effect of different antiplatelet strategies on clinical outcomes after
coronary artery bypass grafting. Design Five year follow-up of randomised Different …

Vein grafts are widely used for coronary artery bypass grafting and hemodialysis access, but
restenosis remains the" Achilles' heel" of these treatments. An extravascular stent is one …

Coronary artery bypass grafting (CABG) is the most frequently performed cardiac surgery
worldwide. The reported incidence of graft failure ranges between 10% and 50 …

Saphenous vein bypass grafting is an effective technique used to treat peripheral arterial
disease (PAD). However, restenosis is the major clinical challenge for the graft vessel …

The contractile-synthetic phenotypic conversion of vascular smooth muscle cells (VSMCs)
plays a key role in atherosclerosis, vascular restenosis, and hypertension. Our previous …

Blood vessels are subjected to complex biomechanical loads, primarily from pressure-driven
blood flow. Abnormal loading associated with vascular grafts, arising from altered …

Dual antiplatelet therapy (DAPT) is recommended after acute coronary syndrome events, but
aspirin as single antiplatelet therapy remains the cornerstone of antithrombotic therapy in …