Specialized pro-resolving lipid mediators (SPMs) such as lipoxins or resolvins are formed by
the consecutive action of 5-lipoxygenase (5-LO, ALOX5) and different types of arachidonic …

Despite the overwhelming female-predominance in chronic pain disorders, preclinical pain
studies have historically excluded females as research subjects. Male-biased explanations …

The newly identified bacterium Dysosmobacter welbionis J115 T improves host metabolism
in high-fat diet (HFD)-fed mice. To investigate mechanisms, we used targeted lipidomics to …

Resolvin D5 (RvD5) is a lipid mediator that has been reported to present anti-inflammatory
and pro-resolution properties. Evidence also supports its capability to enhance reactive …

Abstract Resolvin D5 (RvD5) is a specialized pro-resolving lipid mediator with potent anti-
inflammatory and analgesic properties. Orofacial pain conditions, especially those that are …

Background Although previous studies have identified specific circulating inflammatory
markers associated with the risk of mortality, they have often overlooked the broader impact …

Achieving regeneration in humans has been a long-standing goal of many researchers.
Whereas amphibians like the axolotl (Ambystoma mexicanum) are capable of regenerating …

The resolution of inflammation, as part of standard host defense mechanism, is the process
to guarantee timely termination of inflammatory responses and eventual restoration of tissue …

Abstract Fatal “cytokine storms (CS)” observed in critically ill COVID-19 patients are
consequences of dysregulated host immune system and over-exuberant inflammatory …

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) supplements have
exhibited inconsistent effects on cancer risk, and their potential efficacy as cancer preventive …