Nonalcoholic fatty liver disease and cardiovascular disease: a review of shared cardiometabolic risk factors

E Muzurović, CCH Peng, MJ Belanger, D Sanoudou… - …, 2022 - Am Heart Assoc
The prevalence of nonalcoholic fatty liver disease (NAFLD) is rising. NAFLD/nonalcoholic
steatohepatitis (NASH) is associated not only with hepatic morbidity and mortality but also …

Ferroptosis, a new pathogenetic mechanism in cardiometabolic diseases and cancer: Is there a role for statin therapy?

A Sahebkar, Z Foroutan, N Katsiki, T Jamialahmadi… - Metabolism, 2023 - Elsevier
One of the newly recognized types of cell death is ferroptosis which is related to the
accumulation of iron and lipid-reactive oxygen species. Ferroptosis is considered a …

NAFLD and thyroid function: pathophysiological and therapeutic considerations

E Hatziagelaki, SA Paschou, M Schön… - Trends in Endocrinology …, 2022 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is a worldwide rising challenge because of hepatic,
but also extrahepatic, complications. Thyroid hormones are master regulators of energy and …

Glucagon-like peptide-1 receptor agonists and dual glucose-dependent insulinotropic polypeptide/glucagon-like peptide-1 receptor agonists in the treatment of …

EM Muzurović, Š Volčanšek… - Journal of …, 2022 - journals.sagepub.com
The obesity pandemic is accompanied by increased risk of developing metabolic syndrome
(MetS) and related conditions: non-alcoholic fatty liver disease (NAFLD)/non-alcoholic …

Steatotic liver disease: pathophysiology and emerging pharmacotherapies

M Kokkorakis, E Muzurović, Š Volčanšek… - Pharmacological …, 2024 - ASPET
Steatotic liver disease (SLD) displays a dynamic and complex disease phenotype.
Consequently, the metabolic dysfunction-associated steatotic liver disease …

Sarcopenia, sarcopenic obesity and nonalcoholic fatty liver disease

SA Polyzos, ID Vachliotis, CS Mantzoros - Metabolism, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD), sarcopenia and sarcopenic obesity (SO) are
highly prevalent conditions that may coexist, especially in the aging population, without any …

Time to transition from a negative nomenclature describing what NAFLD is not, to a novel, pathophysiology-based, umbrella classification of fatty liver disease (FLD)

L Valenzuela-Vallejo, CS Mantzoros - Metabolism, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a definition of a prevalent condition that has
been given a name describing what the disease is not, mainly due to gaps in the …

Precision medicine in fatty liver disease/non-alcoholic fatty liver disease

L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

NAFLD, MAFLD, and beyond: one or several acronyms for better comprehension and patient care

P Portincasa - Internal and Emergency Medicine, 2023 - Springer
The term non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common
type of chronic liver disease. NAFLD points to excessive hepatic fat storage and no evidence …

Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression in male mice

H Xia, CR Dufour, Y Medkour, C Scholtes… - Nature …, 2023 - nature.com
Nonalcoholic steatohepatitis (NASH) is epidemiologically associated with obesity and
diabetes and can lead to liver cirrhosis and hepatocellular carcinoma if left untreated. The …