[HTML][HTML] Simulation-based approaches for drug delivery systems: Navigating advancements, opportunities, and challenges

I Salahshoori, M Golriz, MAL Nobre, S Mahdavi… - Journal of Molecular …, 2024 - Elsevier
Efficient drug delivery systems (DDSs) play a pivotal role in ensuring pharmaceuticals'
targeted and effective administration. However, the intricate interplay between drug …

Anti-tumor immune potentiation targets-engineered nanobiotechnologies: design principles and applications

R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2024 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …

Brain co‐delivery of temozolomide and cisplatin for combinatorial glioblastoma chemotherapy

Y Zou, Y Wang, S Xu, Y Liu, J Yin… - Advanced …, 2022 - Wiley Online Library
Glioblastoma (GBM) is an intractable malignancy with high recurrence and mortality.
Combinatorial therapy based on temozolomide (TMZ) and cisplatin (CDDP) shows …

Bionanoparticles in cancer imaging, diagnosis, and treatment

Y Li, Q Bao, S Yang, M Yang, C Mao - View, 2022 - Wiley Online Library
Biological molecules such as DNA, proteins, and lipids can be assembled into naturally
existing nanoparticles, such as bacterial viruses (also called bacteriophages or phages) …

Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR

AQ Zhang, A Hostetler, LE Chen… - Nature Biomedical …, 2023 - nature.com
The effectiveness of chimaeric antigen receptor (CAR) T cell therapies for solid tumours is
hindered by difficulties in the selection of an effective target antigen, owing to the …

Smart nanosensitizers for activatable sono‐photodynamic immunotherapy of tumors by redox‐controlled disassembly

L Liu, J Zhang, R An, Q Xue, X Cheng, Y Hu… - Angewandte …, 2023 - Wiley Online Library
Tumor‐targeted and stimuli‐activatable nanosensitizers are highly desirable for cancer
theranostics. However, designing smart nanosensitizers with multiple imaging signals and …

Engineering supramolecular nanomedicine for targeted near infrared-triggered mitochondrial dysfunction to potentiate cisplatin for efficient chemophototherapy

W Zhang, XF Du, B Liu, C Li, J Long, MX Zhao, Z Yao… - ACS …, 2021 - ACS Publications
Combinatorial cancer therapies based on nanomedicine have emerged as a promising
strategy to achieve potentiated treatment efficiency. Herein, cisplatin (CDDP) prodrug (Pt …

Nanoengineered neutrophils as a cellular sonosensitizer for visual sonodynamic therapy of malignant tumors

L Sun, J Zhou, T Luo, J Wang, L Kang… - Advanced …, 2022 - Wiley Online Library
The rapid evolution of cell‐based theranostics has attracted extensive attention due to their
unique advantages in biomedical applications. However, the inherent functions of cells …

Aloe derived nanovesicle as a functional carrier for indocyanine green encapsulation and phototherapy

L Zeng, H Wang, W Shi, L Chen, T Chen… - Journal of …, 2021 - Springer
Background Cancer is one of the devastating diseases in the world. The development of
nanocarrier provides a promising perspective for improving cancer therapeutic efficacy …

Structural determinants of stimuli-responsiveness in amphiphilic macromolecular nano-assemblies

H Liu, HH Lu, Y Alp, R Wu, S Thayumanavan - Progress in Polymer …, 2024 - Elsevier
Stimuli-responsive nano-assemblies from amphiphilic macromolecules could undergo
controlled structural transformations and generate diverse macroscopic phenomenon under …