The Wnt pathway: from signaling mechanisms to synthetic modulators

EY Rim, H Clevers, R Nusse - Annual review of biochemistry, 2022 - annualreviews.org
The Wnt pathway is central to a host of developmental and disease-related processes. The
remarkable conservation of this intercellular signaling cascade throughout metazoan …

The mechanics of plant morphogenesis

E Coen, DJ Cosgrove - Science, 2023 - science.org
Understanding the mechanism by which patterned gene activity leads to mechanical
deformation of cells and tissues to create complex forms is a major challenge for …

Mechanical conflict caused by a cell-wall-loosening enzyme activates de novo shoot regeneration

V Varapparambath, MM Mathew, AP Shanmukhan… - Developmental Cell, 2022 - cell.com
Cellular heterogeneity is a hallmark of multicellular organisms. During shoot regeneration
from undifferentiated callus, only a select few cells, called progenitors, develop into shoot …

PIN-FORMED and PIN-LIKES auxin transport facilitators

M Sauer, J Kleine-Vehn - Development, 2019 - journals.biologists.com
The phytohormone auxin influences virtually all aspects of plant growth and development.
Auxin transport across membranes is facilitated by, among other proteins, members of the …

Plants use molecular mechanisms mediated by biomolecular condensates to integrate environmental cues with development

S Field, GJ Jang, C Dean, LC Strader, SY Rhee - The Plant Cell, 2023 - academic.oup.com
This review highlights recent literature on biomolecular condensates in plant development
and discusses challenges for fully dissecting their functional roles. Plant developmental …

The bryophytes Physcomitrium patens and Marchantia polymorpha as model systems for studying evolutionary cell and developmental biology in plants

S Naramoto, Y Hata, T Fujita, J Kyozuka - The Plant Cell, 2022 - academic.oup.com
Bryophytes are nonvascular spore-forming plants. Unlike in flowering plants, the
gametophyte (haploid) generation of bryophytes dominates the sporophyte (diploid) …

Fifteen compelling open questions in plant cell biology

AHK Roeder, MS Otegui, R Dixit, CT Anderson… - The Plant …, 2022 - academic.oup.com
As scientists, we are at least as excited about the open questions—the things we do not
know—as the discoveries. Here, we asked 15 experts to describe the most compelling open …

Head-to-tail polymerization in the assembly of biomolecular condensates

M Bienz - Cell, 2020 - cell.com
Clustering of macromolecules is a fundamental cellular device underlying diverse biological
processes that require high-avidity binding to effectors and substrates. Often, this involves a …

Cycling in a crowd: Coordination of plant cell division, growth, and cell fate

R Sablowski, C Gutierrez - The Plant Cell, 2022 - academic.oup.com
The reiterative organogenesis that drives plant growth relies on the constant production of
new cells, which remain encased by interconnected cell walls. For these reasons, plant …

Arabidopsis stomatal lineage cells establish bipolarity and segregate differential signaling capacity to regulate stem cell potential

ES Wallner, L Dolan, DC Bergmann - Developmental cell, 2023 - cell.com
Cell polarity combined with asymmetric cell divisions (ACDs) generates cellular diversity. In
the Arabidopsis stomatal lineage, a single cortical polarity domain marked by BASL orients …