The emerging role of exosome-derived non-coding RNAs in cancer biology

Q Fan, L Yang, X Zhang, X Peng, S Wei, D Su, Z Zhai… - Cancer letters, 2018 - Elsevier
Exosomes are a new means of intercellular information exchange that have aroused great
research interest. Long neglected in research, exosomes were deemed nonfunctional …

Glutathione “redox homeostasis” and its relation to cardiovascular disease

VP Bajic, C Van Neste, M Obradovic… - Oxidative medicine …, 2019 - Wiley Online Library
More people die from cardiovascular diseases (CVD) than from any other cause.
Cardiovascular complications are thought to arise from enhanced levels of free radicals …

[HTML][HTML] Hypoxia-induced lncRNA-AC020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating PKM2/HIF-1α axis

Q Hua, B Mi, F Xu, J Wen, L Zhao, J Liu, G Huang - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Non-small cell lung cancer (NSCLC) is a deadly disease with a hallmark of
aberrant metabolism. The mechanism of glycolysis associated lncRNA underlying the …

[HTML][HTML] Exosome-encapsulated microRNAs as circulating biomarkers for colorectal cancer

S Yan, B Han, S Gao, X Wang, Z Wang, F Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Currently available studies have suggested that a number of exosome-encapsulated
microRNAs (miRNAs) are recognized as stable biomarkers for cancers. However, little is …

HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development

L Zhou, Y Wang, M Zhou, Y Zhang, P Wang, X Li… - Nature …, 2018 - nature.com
Glycolytic reprogramming is a typical feature of many cancers; however, key regulators of
glucose metabolism reengineering are poorly understood, especially in cutaneous …

Loss of function of miR-342-3p results in MCT1 over-expression and contributes to oncogenic metabolic reprogramming in triple negative breast cancer

SL Romero-Cordoba, S Rodriguez-Cuevas… - Scientific reports, 2018 - nature.com
Triple-negative breast cancer (TNBC) is a heterogeneous and aggressive neoplasia lacking
the expression of hormonal receptors and human epidermal growth factor receptor-2 …

Decoding the regulatory roles of non-coding RNAs in cellular metabolism and disease

Y Zong, X Wang, B Cui, X Xiong, A Wu, C Lin, Y Zhang - Molecular Therapy, 2023 - cell.com
Non-coding RNAs, including long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and
circular RNAs (circRNAs), are being studied extensively in a variety of fields. Their roles in …

Long noncoding RNAs coordinate functions between mitochondria and the nucleus

Y Dong, T Yoshitomi, JF Hu, J Cui - Epigenetics & chromatin, 2017 - Springer
In animal cells, mitochondria are the primary powerhouses and metabolic factories. They
also contain genomes and can produce mitochondrial-specific nucleic acids and proteins …

regulation of the cancer epigenome by long non-coding RNAs

ME Forrest, AM Khalil - Cancer Letters, 2017 - Elsevier
Long non-coding RNAs have emerged as highly versatile players in the regulation of gene
expression in development and human disease, particularly cancer. Hundreds of lncRNAs …

Long non-coding RNA and acute leukemia

GM Cruz-Miranda, A Hidalgo-Miranda… - International journal of …, 2019 - mdpi.com
Acute leukemia (AL) is the main type of cancer in children worldwide. Mortality by this
disease is high in developing countries and its etiology remains unanswered. Evidences …