Genetic studies of alcohol dependence in the context of the addiction cycle

MT Reilly, A Noronha, D Goldman, GF Koob - Neuropharmacology, 2017 - Elsevier
Family, twin and adoption studies demonstrate clearly that alcohol dependence and alcohol
use disorders are phenotypically complex and heritable. The heritability of alcohol use …

Kappa opioid receptor signaling in the brain: Circuitry and implications for treatment

NA Crowley, TL Kash - Progress in Neuro-Psychopharmacology and …, 2015 - Elsevier
Kappa opioid receptors (KORs) in the central nervous system have been known to be
important regulators of a variety of psychiatry illnesses, including anxiety and addiction, but …

[图书][B] Alcohol: Neurobiology of Addiction

GF Koob, MA Arends, ML McCracken, M Le Moal - 2021 - books.google.com
A current survey and synthesis of the most important findings in our understanding of the
neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series …

[HTML][HTML] AddictGene: An integrated knowledge base for differentially expressed genes associated with addictive substance

L Shi, Y Wang, C Li, K Zhang, Q Du, M Zhao - Computational and Structural …, 2021 - Elsevier
Addiction, a disorder of maladaptive brain plasticity, is associated with changes in numerous
gene expressions. Nowadays, high-throughput sequencing data on addictive substance …

Hypermethylation of the κ1 opioid receptor promoter in Chinese heroin and methamphetamine addicts

H Ji, G Liu, X Xu, H Liu, L Xu, H Hu… - Experimental and …, 2018 - spandidos-publications.com
Heroin and methamphetamine (METH) addiction continues to be a major social, economic
and therapeutic problem worldwide. The opioid pathway may mediate the effects of …

Prodynorphin (PDYN) gene polymorphisms in Turkish patients with methamphetamine use disorder, changes in PDYN serum levels in withdrawal and the relationship …

G Şenormancı, C Turan, SK Çelik, A Celik… - Journal of Ethnicity in …, 2022 - Taylor & Francis
Aim of the study is to compare prodynorphin (PDYN) rs1997794, rs1022563, rs6045819,
rs2235749 polymorphisms in individuals with methamphetamine use disorder (MD) to that of …

[引用][C] Alcohol: Neurobiology of Addiction

M Le Moal - 2021 - Elsevier