Low frequency systemic hemodynamic “noise” in resting state BOLD fMRI: characteristics, causes, implications, mitigation strategies, and applications

Y Tong, LM Hocke, BB Frederick - Frontiers in neuroscience, 2019 - frontiersin.org
Advances in functional magnetic resonance imaging (fMRI) acquisition have improved
signal to noise to the point where the physiology of the subject is the dominant noise source …

Resting‐State fMRI: Emerging Concepts for Future Clinical Application

S Amemiya, H Takao, O Abe - Journal of Magnetic Resonance …, 2024 - Wiley Online Library
Resting‐state functional magnetic resonance imaging (rsfMRI) has been developed as a
method of investigating spontaneous neural activity. Based on its low‐frequency signal …

[HTML][HTML] Evaluation of 2D multiband EPI imaging for high-resolution, whole-brain, task-based fMRI studies at 3T: Sensitivity and slice leakage artifacts

N Todd, S Moeller, EJ Auerbach, E Yacoub, G Flandin… - Neuroimage, 2016 - Elsevier
Functional magnetic resonance imaging (fMRI) studies that require high-resolution whole-
brain coverage have long scan times that are primarily driven by the large number of thin …

Cerebrovascular reactivity mapping without gas challenges

P Liu, Y Li, M Pinho, DC Park, BG Welch, H Lu - Neuroimage, 2017 - Elsevier
Cerebrovascular reactivity (CVR), the ability of cerebral vessels to dilate or constrict, has
been shown to provide valuable information in the diagnosis and treatment evaluation of …

[HTML][HTML] Vascular physiology drives functional brain networks

MG Bright, JR Whittaker, ID Driver, K Murphy - NeuroImage, 2020 - Elsevier
We present the first evidence for vascular regulation driving fMRI signals in specific
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …

[HTML][HTML] Comparing end-tidal CO2, respiration volume per time (RVT), and average gray matter signal for mapping cerebrovascular reactivity amplitude and delay with …

KM Zvolanek, S Moia, JN Dean, RC Stickland… - NeuroImage, 2023 - Elsevier
Cerebrovascular reactivity (CVR), defined as the cerebral blood flow response to a
vasoactive stimulus, is an imaging biomarker with demonstrated utility in a range of diseases …

Correcting for blood arrival time in global mean regression enhances functional connectivity analysis of resting state fMRI-BOLD signals

SB Erdoğan, Y Tong, LM Hocke, KP Lindsey… - Frontiers in human …, 2016 - frontiersin.org
Resting state functional connectivity analysis is a widely used method for mapping intrinsic
functional organization of the brain. Global signal regression (GSR) is commonly employed …

Perfusion information extracted from resting state functional magnetic resonance imaging

Y Tong, KP Lindsey, LM Hocke… - Journal of Cerebral …, 2017 - journals.sagepub.com
It is widely known that blood oxygenation level dependent (BOLD) contrast in functional
magnetic resonance imaging (fMRI) is an indirect measure for neuronal activations through …

The resting-state fMRI arterial signal predicts differential blood transit time through the brain

Y Tong, J Yao, JJ Chen… - Journal of Cerebral …, 2019 - journals.sagepub.com
Previous studies have found that aperiodic, systemic low-frequency oscillations (sLFOs) are
present in blood-oxygen-level-dependent (BOLD) data. These signals are in the same low …

The role of cerebrovascular-reactivity mapping in functional MRI: calibrated fMRI and resting-state fMRI

JJ Chen, CJ Gauthier - Frontiers in physiology, 2021 - frontiersin.org
Task and resting-state functional MRI (fMRI) is primarily based on the same blood-
oxygenation level-dependent (BOLD) phenomenon that MRI-based cerebrovascular …