Stepwise cell culture process intensification for high-productivity and cost-effective commercial manufacturing of a Mabcalin™ bispecifics
J Zhang, W Cao, L Yu, Y Cui, K Xu, J Tian… - Biochemical …, 2024 - Elsevier
Process intensification and media optimization, as a crucial step for improving productivity
and manufacturing cost of goods (COG), set the stage for commercialization readiness and …
and manufacturing cost of goods (COG), set the stage for commercialization readiness and …
Raman‐controlled pyruvate feeding to control metabolic activity and product quality in continuous biomanufacturing
P Romann, S Schneider, D Tobler… - Biotechnology …, 2024 - Wiley Online Library
Background Despite technological advances ensuring stable cell culture perfusion
operation over prolonged time, reaching a cellular steady‐state metabolism remains a …
operation over prolonged time, reaching a cellular steady‐state metabolism remains a …
A comparison of different intensified upstream processes highlighting the advantage of WuXi Biologics' Ultra‐high Productivity platform (WuXiUPTM) in improved …
X Zheng, M Fang, Y Zou, S Wang… - Biotechnology …, 2024 - Wiley Online Library
Abstract WuXiUPTM, WuXi Biologics' Ultra‐high Productivity platform, is an intensified and
integrated continuous bioprocess platform developed for production of various biologics …
integrated continuous bioprocess platform developed for production of various biologics …
Advancing continuous biomanufacturing: Quality control and process intensification strategies for perfusion cell culture
P Romann - 2023 - repositum.tuwien.at
Emerging product classes, like fusion proteins, antibody-drug conjugates (ADCs), and
bispecifics, are reshaping the landscape of biologics. Biosimilars have also entered the …
bispecifics, are reshaping the landscape of biologics. Biosimilars have also entered the …