Advances in the last decade for the synthesis of the imidazo [1, 2-a] pyridine scaffold from
various substrates employing approaches such as multicomponent reactions, tandem …

Imidazo [1, 2‐a] pyridine is a well‐known scaffold in many marketed drugs, such as
Zolpidem, Minodronic acid, Miroprofen and DS‐1 and it also serves as a broadly applied …

Abstract The Groebke–Blackburn–Bienaymé reaction (GBBR) is used for the one-pot
synthesis of therapeutically relevant fused imidazoles bridgehead nitrogen heterocyclic …

Quinoline is one of the most widely investigated scaffolds by synthetic chemists because of
its medicinal importance. A wide range of metal-catalyzed, metal-free, multi-step or domino …

In recent time, diversity-oriented synthesis of small chemical entities has been emerged as a
possible tool for exploring the intersections between chemistry and biology. These small …

Fused tetracyclic systems containing a quinoline nucleus represent an important class of
heterocyclic bioactive natural products and pharmaceuticals because of their significant and …

As one of the most widely investigated compound skeleton, quinolines possess important
medicinal and biological activities. As such, a great number of literatures, including reviews …

A series of imido-heterocycle compounds were designed, synthesized, characterized, and
evaluated for the anticancer potential using breast (MCF-7 and MDA-MB-231), pancreatic …

3-iodo-1 H-pyrrolo [3′, 2′: 4, 5] imidazo-[1, 2-a] pyridines and [1, 2-b] pyridazines were
prepared following Groebke–Blackburn–Bienaymé MCR combined with I2-promoted …

The design and synthesis of a quality compound library containing a small number of
skeletally diverse scaffolds, whose members rapidly deliver new chemical probes active …