Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches
TBI has been one of the top causes of death and morbidity worldwide, yet despite enormous
efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …
efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …
On the common journey of neural cells through ischemic brain injury and Alzheimer's disease
J Kriska, Z Hermanova, T Knotek, J Tureckova… - International Journal of …, 2021 - mdpi.com
Ischemic brain injury and Alzheimer's disease (AD) both lead to cell death in the central
nervous system (CNS) and thus negatively affect particularly the elderly population. Due to …
nervous system (CNS) and thus negatively affect particularly the elderly population. Due to …
Pharmacological inhibition of transient receptor potential vanilloid 4 reduces vasogenic edema after traumatic brain injury in mice
S Michinaga, K Onishi, K Shimizu… - Biological and …, 2021 - jstage.jst.go.jp
Vasogenic edema results from blood–brain barrier (BBB) disruption after traumatic brain
injury (TBI), and although it can be fatal, no promising therapeutic drugs have been …
injury (TBI), and although it can be fatal, no promising therapeutic drugs have been …
Transient receptor potential vanilloid 4: A double-edged sword in the central nervous system
M Zeng, S Kong, T Chen, B Peng - Molecular Neurobiology, 2023 - Springer
Transient receptor potential vanilloid 4 (TRPV4) is a nonselective cation channel that can be
activated by diverse stimuli, such as heat, mechanical force, hypo-osmolarity, and …
activated by diverse stimuli, such as heat, mechanical force, hypo-osmolarity, and …
Characterization of the lncRNA-miRNA-mRNA regulatory network to reveal potential functional competing endogenous RNAs in traumatic brain injury
J Yu, Z Lu, R Liu, P Wang, H Ma, Y Zhao - Frontiers in Neuroscience, 2023 - frontiersin.org
Traumatic brain injury (TBI) is one of the most common acute central nervous system injury
diseases. Given the medical and socio-economic burdens of TBI patients, the pathogenesis …
diseases. Given the medical and socio-economic burdens of TBI patients, the pathogenesis …
Potential molecular mechanism of motherwort in the treatment of nerve injury based on network pharmacology
Z Qian, GUO Yuchen, D Shanshan, Z Yuefan… - 药学实践与 …, 2022 - yxsj.smmu.edu.cn
Objective To explore the mechanism of motherwort in the treatment of nerve injury. Methods
The active components of motherwort were obtained by searching TCMSP and BATMAN …
The active components of motherwort were obtained by searching TCMSP and BATMAN …
Systems pharmacology
TJ Maher - Translational Systems Medicine and Oral Disease, 2020 - Elsevier
While development of the individual disciplines in the physical, chemical, and biological
sciences has led to substantial discoveries in their respective fields that have influenced …
sciences has led to substantial discoveries in their respective fields that have influenced …