Porosity and diffusion in biological tissues. Recent advances and further perspectives

R Penta, L Miller, A Grillo, A Ramírez-Torres… - Constitutive modelling of …, 2020 - Springer
We present a review of porosity and diffusion in biological tissues from different
perspectives. We first introduce the topic by illustrating experimental evidence related to …

A formulation of volumetric growth as a mechanical problem subjected to non-holonomic and rheonomic constraint

A Grillo, S Di Stefano - Mathematics and Mechanics of Solids, 2023 - journals.sagepub.com
Starting from a reformulation of the mass balance law based on the Bilby–Kröner–Lee (BKL)
decomposition of the deformation gradient tensor, we study some peculiar mechanical …

Coupling solid and fluid stresses with brain tumour growth and white matter tract deformations in a neuroimaging-informed model

G Lucci, A Agosti, P Ciarletta, C Giverso - Biomechanics and Modeling in …, 2022 - Springer
Brain tumours are among the deadliest types of cancer, since they display a strong ability to
invade the surrounding tissues and an extensive resistance to common therapeutic …

Coupling among deformation, fluid flow, structural reorganisation and fibre reorientation in fibre-reinforced, transversely isotropic biological tissues

E Crevacore, S Di Stefano, A Grillo - International Journal of Non-Linear …, 2019 - Elsevier
We highlight some mechanical aspects of the coupling among deformation, fluid flow,
structural evolution, and reorientation of fibres in fibre-reinforced, hydrated, soft biological …

An Approach to Growth Mechanics Based on the Analytical Mechanics of Nonholonomic Systems

A Grillo, A Pastore, S Di Stefano - Journal of Elasticity, 2025 - Springer
Motivated by the convenience, in some biomechanical problems, of interpreting the mass
balance law of a growing medium as a nonholonomic constraint on the time rate of a …

An a posteriori approach to the mechanics of volumetric growth

A Grillo, S Di Stefano - Mathematics and Mechanics of Complex Systems, 2023 - msp.org
This work focuses on the study of volumetric growth, ie, the branch of biomechanics that
investigates the variation of mass of biological systems, modeled as continuous media. Our …

Two-scale, non-local diffusion in homogenised heterogeneous media

A Ramírez-Torres, R Penta, A Grillo - Archive of Applied Mechanics, 2021 - Springer
We study how and to what extent the existence of non-local diffusion affects the transport of
chemical species in a composite medium. For our purposes, we prescribe the mass flux to …

Influence of non-local diffusion in avascular tumour growth

A Ramírez-Torres, S Di Stefano… - … and Mechanics of …, 2021 - journals.sagepub.com
The availability and evolution of chemical agents play an important role in the growth of a
tumour and, therefore, the mathematical description of their consumption is of special …

Mathematical modelling of residual-stress based volumetric growth in soft matter

R Huang, RW Ogden, R Penta - Journal of Elasticity, 2021 - Springer
Growth in nature is associated with the development of residual stresses and is in general
heterogeneous and anisotropic at all scales. Residual stress in an unloaded configuration of …

Anelastic reorganisation of fibre-reinforced biological tissues

S Di Stefano, M Carfagna, MM Knodel… - … and Visualization in …, 2019 - Springer
In this work, we contribute to the study of the structural reorganisation of biological tissues in
response to mechanical stimuli. We specialise our investigation to a class of hydrated soft …