Myostatin, also known as growth differentiation factor 8, a member of the transforming
growth factor‐beta super‐family, is a negative regulator of muscle development. Myostatin …

The horse was domesticated only 5.5 KYA, thousands of years after dogs, cattle, pigs,
sheep, and goats. The horse nonetheless represents the domestic animal that most …

The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

Selective breeding for speed in the racehorse has resulted in an unusually high frequency of
the C-variant (g. 66493737C/T) at the myostatin gene (MSTN) in cohorts of the …

Thoroughbred horses have been selected for racing performance for more than 400 years.
Despite continued selection, race times have not improved significantly during the past 60 …

Thoroughbred horses are finely-tuned athletes with a high aerobic capacity relative to
skeletal muscle mass, attributable to centuries of genetic selection for speed and stamina …

The Thoroughbred breed was formed by crossing Oriental horse breeds and British native
horses and is currently used in horseracing worldwide. In this study, we constructed a single …

Gene doping, an activity which abuses and misuses gene therapy, is a major concern in
sports and horseracing industries. Effective methods capable of detecting and monitoring …

Myostatin is a member of the transforming growth factor-β family with a key role in inhibition
of muscle growth by negative regulation of both myoblast proliferation and differentiation …

Two variants in the equine myostatin gene (MSTN), including a T/C SNP in the first intron
and a 227‐bp SINE insertion in the promoter, are associated with muscle fiber type …