Resveratrol: A double-edged sword in health benefits

B Salehi, AP Mishra, M Nigam, B Sener, M Kilic… - Biomedicines, 2018 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) belongs to polyphenols' stilbenoids group,
possessing two phenol rings linked to each other by an ethylene bridge. This natural …

Role of resveratrol in regulation of cellular defense systems against oxidative stress

VL Truong, M Jun, WS Jeong - Biofactors, 2018 - Wiley Online Library
Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and
their commercial products such as red wine. It has been demonstrated to exhibit a variety of …

Chemical and molecular mechanisms of antioxidants: experimental approaches and model systems

JM Lü, PH Lin, Q Yao, C Chen - Journal of cellular and …, 2010 - Wiley Online Library
Introduction• Free radical scavenging‐Scavenging superoxide and other ROS‐Scavenging
hydroxyl radical and other ROS‐Stable radical scavenging• Metal ion (Fe2+, Fe3+, Cu2+ …

The pros and cons of phytoestrogens

HB Patisaul, W Jefferson - Frontiers in neuroendocrinology, 2010 - Elsevier
Phytoestrogens are plant derived compounds found in a wide variety of foods, most notably
soy. A litany of health benefits including a lowered risk of osteoporosis, heart disease, breast …

Resveratrol and health–a comprehensive review of human clinical trials

JM Smoliga, JA Baur… - Molecular nutrition & food …, 2011 - Wiley Online Library
In the past decade, the small polyphenol resveratrol has received widespread attention as
either a potential therapy or as a preventive agent for numerous diseases. Studies using …

Beneficial action of resveratrol: How and why?

GT Diaz-Gerevini, G Repossi, A Dain, MC Tarres… - Nutrition, 2016 - Elsevier
Flavonoid resveratrol modulates the transcription factor NF-κB; inhibits the cytochrome P450
isoenzyme CYP1 A1; suppresses the expression and activity of cyclooxygenase enzymes; …

Polyphenols as antioxidant/pro-oxidant compounds and donors of reducing species: relationship with human antioxidant metabolism

CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Processes, 2023 - mdpi.com
In this review, we have focused mainly on the study of their antioxidant and pro-oxidant
capacity, and the analysis of the oxidation of the catechol group to o-quinone. The redox …

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

SS Karuppagounder, JT Pinto, H Xu, HL Chen… - Neurochemistry …, 2009 - Elsevier
Resveratrol, a polyphenol found in red wine, peanuts, soy beans, and pomegranates,
possesses a wide range of biological effects. Since resveratrol's properties seem ideal for …

Naturally occurring phytochemicals for the prevention of Alzheimer's disease

J Kim, HJ Lee, KW Lee - Journal of neurochemistry, 2010 - Wiley Online Library
J. Neurochem.(2010) 112, 1415–1430. Abstract Alzheimer's disease (AD) is an age‐related
neurodegenerative disease increasingly recognized as one of the most important medical …

[PDF][PDF] Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPx1) and …

G Spanier, H Xu, N Xia, S Tobias, S Deng… - J Physiol …, 2009 - researchgate.net
Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red
wine's potential to prevent human cardiovascular disease. In addition to its known (direct) …