Cancer is the second leading cause of mortality globally which remains a continuing threat
to human health today. Drug insensitivity and resistance are critical hurdles in cancer …

Cancer, also known as malignant neoplasm, is a dreadful disease which involves abnormal
cell growth having the potential to invade or spread to other parts of the body …

Currently, cancer metastases remain a major clinical problem that highlights the importance
of recognition of the metastatic process in cancer diagnosis and treatment. A critical process …

Herein, we describe a highly efficient and eco-friendly protocol for the synthesis of
benzimidazoles, benzothiazoles, and quinoxalines using VOSO 4 as a catalyst in ethanol …

The three-membered ring in 2-(2-pyridyl) azirine-2-carboxylic esters and thioesters can
undergo selective cleavage of either the N–C2 bond under copper (II) catalysis or the C–C …

An iron-catalyzed efficient C–H amination for the construction of imidazole-fused-ring
systems was developed under aerobic conditions. Compared to previous studies, this work …

Benzimidazole and sulfonamide moieties are found in a number of pharmaceutically active
molecules. By incorporating the sulfonamide pharmacophore into the benzimidazole …

A series of colchicine site binding tubulin inhibitors were synthesized by the modification of
the combretastatin pharmacophore. The ring B was replaced by the pharmacologically …

A series of pyrazoline derivatives and corresponding chalcone intermediates with
substituents same as combretastatin‐A4 (CA‐4) conjugated with triazole nucleus has been …

In this study, two series of imidazopyridine‐linked thiazolidinone rings (5a–h and 6a–h)
constituting 16 new compounds were synthesized and tested for their antiproliferative …