Self-Generating nano-emulsification techniques for alternatively-routed, bioavailability enhanced delivery, especially for anti-cancers, anti-diabetics, and …
The self-generating nano-emulsifying drug delivery system (SNEDDS) is among the most
effective approaches to enhance the oral bioavailability of a therapeutic agent, especially of …
effective approaches to enhance the oral bioavailability of a therapeutic agent, especially of …
Novel approach for transdermal delivery of rifampicin to induce synergistic antimycobacterial effects against cutaneous and systemic tuberculosis using a cationic …
A Hussain, MA Altamimi, S Alshehri… - International journal …, 2020 - Taylor & Francis
Purpose This study demonstrated improved transdermal delivery of rifampicin-loaded
cationic nanoemulsion gel to treat systemic and cutaneous tuberculosis using capmul …
cationic nanoemulsion gel to treat systemic and cutaneous tuberculosis using capmul …
Development and evaluations of transdermally delivered luteolin loaded cationic nanoemulsion: In vitro and ex vivo evaluations
MA Altamimi, A Hussain, S Alshehri, SS Imam… - Pharmaceutics, 2021 - mdpi.com
Introduction: Luteolin (LUT) is natural flavonoid with multiple therapeutic potentials and is
explored for transdermal delivery using a nanocarrier system. LUT loaded cationic …
explored for transdermal delivery using a nanocarrier system. LUT loaded cationic …
Solidified SNEDDS for the oral delivery of rifampicin: Evaluation, proof of concept, in vivo kinetics, and in silico GastroPlusTM simulation
The present investigation was performed to develop a rifampicin (RIF)-loaded solidified self-
nanoemulsifying drug delivery system (SNEDDS)(solidified RIF-OF1) for in vitro and in vivo …
nanoemulsifying drug delivery system (SNEDDS)(solidified RIF-OF1) for in vitro and in vivo …
The optimization design of lactoferrin loaded HupA nanoemulsion for targeted drug transport via intranasal route
Y Jiang, C Liu, W Zhai, N Zhuang, T Han… - International journal of …, 2019 - Taylor & Francis
Background Huperzine A (HupA) is a selective acetylcholinesterase inhibitor used to treat
Alzheimer's disease. The existing dosage of HupA lacks brain selectivity and can cause …
Alzheimer's disease. The existing dosage of HupA lacks brain selectivity and can cause …
Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is
anticipated to bring about comprehensive transformations in the pharmaceutical field …
anticipated to bring about comprehensive transformations in the pharmaceutical field …
Mechanistic insights into luteolin-loaded elastic liposomes for transdermal delivery: HSPiP predictive parameters and instrument-based evidence
MA Altamimi, A Hussain, WA Mahdi, SS Imam… - ACS …, 2022 - ACS Publications
We evaluated mechanistic insights into luteolin (LUT)-loaded elastic liposomes (OLEL1)
permeated across rat skin. HSPiP software-based parameters, thermal analysis, infrared …
permeated across rat skin. HSPiP software-based parameters, thermal analysis, infrared …
Quality by design accredited self-nanoemulsifying delivery of ibrutinib for extenuating the fast-fed variability, ameliorating the anticancer activity and oral bioavailability …
Ibrutinib (IB), which is conventionally employed for leukemia exhibits poor aqueous
solubility, poor oral bioavailability and significant food effect with a 2.15-fold increment in …
solubility, poor oral bioavailability and significant food effect with a 2.15-fold increment in …
Liquid crystalline nanoparticles as an ophthalmic delivery system for tetrandrine: development, characterization, and in vitro and in vivo evaluation
R Liu, S Wang, S Fang, J Wang, J Chen… - Nanoscale research …, 2016 - Springer
The purpose of this study was to develop novel liquid crystalline nanoparticles (LCNPs) that
display improved pre-ocular residence time and ocular bioavailability and that can be used …
display improved pre-ocular residence time and ocular bioavailability and that can be used …
Development, optimization, and characterization of a novel tea tree oil nanogel using response surface methodology
P Sinha, S Srivastava, N Mishra, DK Singh… - Drug development …, 2016 - Taylor & Francis
Purpose: To develop and optimize nanoemulsion (NE)-based emulgel (EG) formulation as a
potential vehicle for topical delivery of tea tree oil (TTO). Methodology: Central composite …
potential vehicle for topical delivery of tea tree oil (TTO). Methodology: Central composite …