Radiomics and artificial intelligence in prostate cancer: new tools for molecular hybrid imaging and theragnostics

V Liberini, R Laudicella, M Balma, DG Nicolotti… - European radiology …, 2022 - Springer
In prostate cancer (PCa), the use of new radiopharmaceuticals has improved the accuracy of
diagnosis and staging, refined surveillance strategies, and introduced specific and …

Non-conventional and investigational PET radiotracers for breast cancer: a systematic review

M Balma, V Liberini, M Racca, R Laudicella… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is one of the most common malignancies in women, with high morbidity and
mortality rates. In breast cancer, the use of novel radiopharmaceuticals in nuclear medicine …

Radiomics analysis of 18F-Choline PET/CT in the prediction of disease outcome in high-risk prostate cancer: An explorative study on machine learning feature …

P Alongi, A Stefano, A Comelli, R Laudicella… - European …, 2021 - Springer
Objective The aim of this study was (1) to investigate the application of texture analysis of
choline PET/CT images in prostate cancer (PCa) patients and (2) to propose a machine …

PSMA-and GRPR-targeted PET: results from 50 patients with biochemically recurrent prostate cancer

L Baratto, H Song, H Duan, N Hatami… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Novel radiopharmaceuticals for PET are being evaluated for the diagnosis of biochemical
recurrence (BCR) of prostate cancer (PC). We compared the gastrin-releasing peptide …

Imaging the distribution of gastrin-releasing peptide receptors in cancer

L Baratto, H Duan, H Mäcke… - Journal of Nuclear …, 2020 - Soc Nuclear Med
Targeting tumor-expressed receptors using selective molecules for diagnostic, therapeutic,
or both diagnostic and therapeutic (theragnostic) purposes is a promising approach in …

68Ga-PSMA and 68Ga-DOTA-RM2 PET/MRI in Recurrent Prostate Cancer: Diagnostic Performance and Association with Clinical and Histopathological Data

P Mapelli, S Ghezzo, AM Samanes Gajate, E Preza… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer (PCa) relapse occurs in up to 50% of patients after radical
treatment. Once PCa recurrence is detected, a precise identification of the number and sites …

Correlation of 68Ga-RM2 PET with postsurgery histopathology findings in patients with newly diagnosed intermediate-or high-risk prostate cancer

H Duan, L Baratto, RE Fan… - Journal of Nuclear …, 2022 - Soc Nuclear Med
68Ga-RM2 targets gastrin-releasing peptide receptors (GRPRs), which are overexpressed
in prostate cancer (PC). Here, we compared preoperative 68Ga-RM2 PET to postsurgery …

Novel GRPR-targeting peptide for pancreatic cancer molecular imaging in orthotopic and liver metastasis mouse models

Y Tu, Z Han, R Pan, K Zhou, J Tao, P Liu… - Analytical …, 2023 - ACS Publications
Despite advancements in pancreatic cancer treatment, it remains one of the most lethal
malignancies with extremely poor diagnosis and prognosis. Herein, we demonstrated the …

Radiopharmaceuticals and their applications in medicine

S Zhang, X Wang, X Gao, X Chen, L Li, G Li… - … and Targeted Therapy, 2025 - nature.com
Radiopharmaceuticals involve the local delivery of radionuclides to targeted lesions for the
diagnosis and treatment of multiple diseases. Radiopharmaceutical therapy, which directly …

Prostate Cancer Biochemical Recurrence Resulted Negative on [68Ga]Ga-PSMA-11 but Positive on [18F]Fluoromethylcholine PET/CT

R Laudicella, F La Torre, V Davì, L Crocè, D Aricò… - Tomography, 2022 - mdpi.com
For prostate cancer (PCa) biochemical recurrence (BCR), the primarily suggested imaging
technique by the European Association of Urology (EAU) guidelines is prostate-specific …