Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes

BS Karam, A Chavez-Moreno, W Koh, JG Akar… - Cardiovascular …, 2017 - Springer
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans. Several
risk factors promote AF, among which diabetes mellitus has emerged as one of the most …

The role of advanced glycation end-products in the development of coronary artery disease in patients with and without diabetes mellitus: a review

SL Fishman, H Sonmez, C Basman, V Singh… - Molecular …, 2018 - Springer
Background Traditional risk factors are insufficient to explain all cases of coronary artery
disease (CAD) in patients with diabetes mellitus (DM). Advanced glycation end-products …

Receptor for advanced glycation end products (RAGE) and mechanisms and therapeutic opportunities in diabetes and cardiovascular disease: insights from human …

L Egaña-Gorroño, R López-Díez, G Yepuri… - Frontiers in …, 2020 - frontiersin.org
Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although
extensive strides have been made in the treatments for non-diabetic atherosclerosis and its …

Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential …

NL Reynaert, P Gopal, EPA Rutten… - The international journal …, 2016 - Elsevier
Age-related, non-communicable chronic inflammatory diseases represent the major 21st
century health problem. Especially in Western countries, the prevalence of non …

The AGE-RAGE Axis and the Pathophysiology of Multimorbidity in COPD

NL Reynaert, LEGW Vanfleteren… - Journal of Clinical …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a disease of the airways and lungs due to
an enhanced inflammatory response, commonly caused by cigarette smoking. Patients with …

Catheter ablation of atrial fibrillation in patients with diabetes mellitus: a systematic review and meta-analysis

M Anselmino, M Matta, F D'ascenzo, C Pappone… - Ep …, 2015 - academic.oup.com
Aims Diabetes mellitus (DM) and atrial fibrillation (AF) share pathophysiological links, as
supported by the high prevalence of AF within DM patients. Catheter ablation of AF (AFCA) …

Diabesity in elderly cardiovascular disease patients: Mechanisms and regulators

D García-Vega, JR González-Juanatey… - International journal of …, 2022 - mdpi.com
Cardiovascular disease (CVD) is the leading cause of death in the world. In 2019, 550
million people were suffering from CVD and 18 million of them died as a result. Most of them …

Oxidant and inflammatory mechanisms and targeted therapy in atrial fibrillation: an update

A Gutierrez, DR Van Wagoner - Journal of cardiovascular …, 2015 - journals.lww.com
Atrial fibrillation (AF) is an important cause of stroke and risk factor for heart failure and
death. Current pharmacologic treatments for AF have limited efficacy, and treatments that …

Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip

L Lind, J Sundström, M Stenemo, E Hagström, J Ärnlöv - Heart, 2017 - heart.bmj.com
Background Apart from several established clinical risk factors for atrial fibrillation (AF), a
number of biomarkers have also been identified as potential risk factors for AF. None of …

Glycation and glycosylation in cardiovascular remodeling: focus on advanced glycation end products and O-linked glycosylations as glucose-related pathogenetic …

E Dozio, L Massaccesi… - Journal of clinical medicine, 2021 - mdpi.com
Glycation and glycosylation are non-enzymatic and enzymatic reactions, respectively, of
glucose, glucose metabolites, and other reducing sugars with different substrates, such as …