Functional modulation of chemical mediators in microbial communities

P Stallforth, M Mittag, AA Brakhage, C Hertweck… - Trends in Biochemical …, 2023 - cell.com
Interactions between microorganisms are often mediated by specialized metabolites.
Although the structures and biosynthesis of these compounds may have been elucidated …

Positive associations fuel soil biodiversity and ecological networks worldwide

X Liu, H Chu, O Godoy, K Fan… - Proceedings of the …, 2024 - National Acad Sciences
Microbial interactions are key to maintaining soil biodiversity. However, whether negative or
positive associations govern the soil microbial system at a global scale remains virtually …

Ribosomally derived lipopeptides containing distinct fatty acyl moieties

F Hubrich, NM Bösch, C Chepkirui… - Proceedings of the …, 2022 - National Acad Sciences
Lipopeptides represent a large group of microbial natural products that include important
antibacterial and antifungal drugs and some of the most-powerful known biosurfactants. The …

Exploring nature's battlefield: organismic interactions in the discovery of bioactive natural products

Y Wang, YN Shi, H Xiang, YM Shi - Natural Product Reports, 2024 - pubs.rsc.org
Covering: up to March 2024. Microbial natural products have historically been a cornerstone
for the discovery of therapeutic agents. Advanced (meta) genome sequencing technologies …

Ecological niche-inspired genome mining leads to the discovery of crop-protecting nonribosomal lipopeptides featuring a transient amino acid building block

S Götze, R Vij, K Burow, N Thome… - Journal of the …, 2023 - ACS Publications
Investigating the ecological context of microbial predator–prey interactions enables the
identification of microorganisms, which produce multiple secondary metabolites to evade …

Charting the lipopeptidome of nonpathogenic Pseudomonas

C Cesa-Luna, N Geudens, L Girard, V De Roo… - Msystems, 2023 - Am Soc Microbiol
ABSTRACT A major source of pseudomonad-specialized metabolites is the nonribosomal
peptide synthetases (NRPSs) assembling siderophores and lipopeptides. Cyclic …

Bacterial endosymbionts protect beneficial soil fungus from nematode attack

H Büttner, SP Niehs… - Proceedings of the …, 2021 - National Acad Sciences
Fungi of the genus Mortierella occur ubiquitously in soils where they play pivotal roles in
carbon cycling, xenobiont degradation, and promoting plant growth. These important fungi …

Predators of soil bacteria in plant and human health

SJ Martins, SJ Taerum, L Triplett… - Phytobiomes …, 2022 - Am Phytopath Society
Soil bacterial predators that use the biomass of bacterial hosts for growth (multiplication),
energy, or replication have the potential to reduce bacterial populations in the wide variety of …

Resistance towards and biotransformation of a Pseudomonas-produced secondary metabolite during community invasion

ML Hansen, Z Dénes, SA Jarmusch… - The ISME …, 2024 - academic.oup.com
The role of antagonistic secondary metabolites produced by Pseudomonas protegens in
suppression of soil-borne phytopathogens has been clearly documented. However, their …

Production, characterization, and potential applications of lipopeptides in food systems: A comprehensive review

S Dini, F Oz, AEDA Bekhit, A Carne… - … reviews in food science …, 2024 - Wiley Online Library
Lipopeptides are a class of lipid–peptide‐conjugated compounds with differing structural
features. This structural diversity is responsible for their diverse range of biological …