Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

Normothermic machine perfusion (NMP) technologies are emerging as an important adjunct
in organ preservation and transplantation. NMP can enable the reduction or avoidance of …

Transplantation is the optimal treatment for most patients with end‐stage kidney disease but
organ shortage is a major challenge. Normothermic machine perfusion (NMP) has been …

The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …

Background. Flavin mononucleotide (FMN), released from damaged mitochondrial complex
I during hypothermic liver perfusion, has been shown to be predictive of 90-day graft loss …

Background The 5-year graft survival rate of donor kidneys transplanted in the
Eurotransplant Senior Program (ESP) is only 47 per cent. Normothermic machine perfusion …

The use of cold preservation solutions to rapidly flush and cool the kidney followed by static
cold storage in ice has been the standard kidney preservation technique for the last 50 y …

The final decision to accept an organ for transplantation remains a subjective one. With
“poor organ quality” commonly cited as a major reason for kidney discard, accurate …

The ever‐widening gap between organ supply and demand has resulted in an organ
shortage crisis that affects patients all over the world. For decades, static cold storage (SCS) …

Pretransplant normothermic machine perfusion (NMP) of donor kidneys offers the unique
opportunity to perform active interventions to an isolated renal graft before transplantation …