With an aging population, there is a proportional increase in the prevalence of intervertebral
disc diseases. Intervertebral disc diseases are the leading cause of lower back pain and …

BACKGROUND CONTEXT The accurate determination of a patient's functional status is
necessary for therapeutic decision-making and to critically appraise treatment efficacy …

Back pain is a common and debilitating disorder with largely unknown underlying biology.
Here we report a genome-wide association study of back pain using diagnoses assigned in …

Objective: The purpose of this study was to examine the relationships between intervertebral
disc degeneration in the lumbar spine, paraspinal muscle morphology, and clinical features …

Background Demographic changes will lead to an increase of elderly people in our
population and consecutively to a higher prevalence of patients suffering from degenerative …

Background and purpose Nonspecific low back pain (LBP) is the most prevalent
musculoskeletal condition in various age ranges and is associated with depression. The aim …

The term 'spinal pain'collectively includes the cervical, thoracic and lumbosacral regions of
the spine. The majority of older people experience spinal pain, and with an increasing …

As a minimally invasive surgery, percutaneous cement discoplasty (PCD) is now
contemplated to treat lumbar disc degeneration disease in elder population. Here, we …

A challenge in understanding chronic musculoskeletal pain is that research is often siloed
between neuroscience, physical therapy/rehabilitation, orthopedics, and rheumatology …

Background The Timed Up and Go (TUG) test, as a measure of objective functional
impairment in lumbar degenerative disk disease (DDD), complements patient-reported …