Applications of alginate microspheres in therapeutics delivery and cell culture: Past, present and future

D Dhamecha, R Movsas, U Sano, JU Menon - International journal of …, 2019 - Elsevier
Polymers are the backbone of pharmaceutical drug delivery. There are several polymers
with varying properties available today for use in different pharmaceutical applications …

Polymers in cell encapsulation from an enveloped cell perspective

P de Vos, HA Lazarjani, D Poncelet… - Advanced drug delivery …, 2014 - Elsevier
In the past two decades, many polymers have been proposed for producing
immunoprotective capsules. Examples include the natural polymers alginate, agarose …

Progress in modern marine biomaterials research

Y Khrunyk, S Lach, I Petrenko, H Ehrlich - Marine Drugs, 2020 - mdpi.com
The growing demand for new, sophisticated, multifunctional materials has brought natural
structural composites into focus, since they underwent a substantial optimization during long …

Calcium alginate gel: a biocompatible and mechanically stable polymer for endovascular embolization

TA Becker, DR Kipke, T Brandon - Journal of Biomedical …, 2001 - Wiley Online Library
The development and optimization of calcium alginate for potential use in endovascular
occlusion was investigated by testing its in vitro and in vivo mechanical stability and …

Controlled delivery of drugs from alginate matrix

A Shilpa, SS Agrawal, AR Ray - Journal of Macromolecular …, 2003 - Taylor & Francis
Alginate is an unbranched binary copolymer constituted of (1, 4) linked α-L-guluronic acid
and β-D-mannuronic acid. It is a high-molecular mass polysaccharide extracted from kelp …

[HTML][HTML] Survival of encapsulated islets: More than a membrane story

U Barkai, A Rotem, P de Vos - World journal of transplantation, 2016 - ncbi.nlm.nih.gov
At present, proven clinical treatments but no cures are available for diabetes, a global
epidemic with a huge economic burden. Transplantation of islets of Langerhans by their …

Research progress in coating techniques of alginate gel polymer for cell encapsulation

G Simó, E Fernández‐Fernández, J Vila‐Crespo… - Carbohydrate …, 2017 - Elsevier
Cell encapsulation is used as a biotechnology tool to solve the technological problems
derived from handling and application of cells in a great range of fields. This involves …

Ultrathin polymeric coatings based on hydrogen‐bonded polyphenol for protection of pancreatic islet cells

V Kozlovskaya, O Zavgorodnya, Y Chen… - Advanced functional …, 2012 - Wiley Online Library
Though transplantation of pancreatic islet cells has emerged as a promising treatment for
Type 1 diabetes its clinical application remains limited due to a number of limitations …

Recent progress in gene delivery using non-viral transfer complexes

WT Godbey, AG Mikos - Journal of Controlled Release, 2001 - Elsevier
The delivery of genetic material into cells is a field that is expanding very rapidly. Non-viral
delivery methods, especially ones that focus on the use of chemical agents complexed with …

Polymeric approaches to reduce tissue responses against devices applied for islet-cell encapsulation

S Hu, P De Vos - Frontiers in bioengineering and biotechnology, 2019 - frontiersin.org
Immunoisolation of pancreatic islets is a technology in which islets are encapsulated in
semipermeable but immunoprotective polymeric membranes. The technology allows for …