Neuroblastoma (NB), a childhood cancer arising from the neural crest, poses significant
clinical challenges, particularly in cases featuring amplification of the MYCN oncogene …

Natural killer (NK) cells play essential roles in the tumor development, diagnosis, and
prognosis of tumors. In this study, we aimed to establish a reliable signature based on …

Objective To develop and validate an 18F-fluorodeoxyglucose (FDG) positron emission
tomography/computed tomography (PET/CT)-based radiomics nomogram for non-invasively …

The heterogeneity of neuroblastoma directly affects the prognosis of patients.
Individualization of patient treatment to improve prognosis is a clinical challenge at this …

Neuroblastoma (NB) is the most common extracranial solid tumor that affects developing
nerve cells in the fetus, infants, and children. miR-124 is a microRNA (miRNA) enriched in …

Gastric cancer (GC) is a major global health issue and one of the leading causes of tumor-
associated mortality worldwide. Autophagy is thought to play a critical role in the …

Dysregulated pre-mRNA splicing and metabolism are two hallmarks of MYC-driven cancers.
Pharmacological inhibition of both processes has been extensively investigated as potential …

Background Colorectal cancer (CRC), the third most prevalent and lethal disease,
accounted for approximately 1.9 million new cases and claimed nearly 861,000 lives in …

The chromodomain helicase DNA binding domain 5 (CHD5) is required for neural
development and plays an important role in the regulation of gene expression. Although …

Background Genetic 1p deletion is reported in 30% of all neuroblastoma and is associated
with the unfavorable prognosis of neuroblastoma. The expressions and prognosis of 1p …