Studying and modelling dynamic biological processes using time-series gene expression data

Z Bar-Joseph, A Gitter, I Simon - Nature Reviews Genetics, 2012 - nature.com
Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …

Dealing with missing values in large-scale studies: microarray data imputation and beyond

T Aittokallio - Briefings in bioinformatics, 2010 - academic.oup.com
High-throughput biotechnologies, such as gene expression microarrays or mass-
spectrometry-based proteomic assays, suffer from frequent missing values due to various …

A time series forest for classification and feature extraction

H Deng, G Runger, E Tuv, M Vladimir - Information Sciences, 2013 - Elsevier
A tree-ensemble method, referred to as time series forest (TSF), is proposed for time series
classification. TSF employs a combination of entropy gain and a distance measure, referred …

Time–frequency time–space LSTM for robust classification of physiological signals

TD Pham - Scientific reports, 2021 - nature.com
Automated analysis of physiological time series is utilized for many clinical applications in
medicine and life sciences. Long short-term memory (LSTM) is a deep recurrent neural …

Functional echo state network for time series classification

Q Ma, L Shen, W Chen, J Wang, J Wei, Z Yu - Information Sciences, 2016 - Elsevier
Echo state networks (ESNs) are a new approach to recurrent neural networks (RNNs) that
have been successfully applied in many domains. Nevertheless, an ESN is a predictive …

Early classification of multivariate temporal observations by extraction of interpretable shapelets

MF Ghalwash, Z Obradovic - BMC bioinformatics, 2012 - Springer
Background Early classification of time series is beneficial for biomedical informatics
problems such including, but not limited to, disease change detection. Early classification …

Early classification of multivariate time series using a hybrid hmm/svm model

MF Ghalwash, D Ramljak… - 2012 IEEE International …, 2012 - ieeexplore.ieee.org
Early classification of time series has been receiving a lot of attention as of late, particularly
in the context of gene expression. In the biomédical realm, early classification can be of …

Natural cubic spline regression modeling followed by dynamic network reconstruction for the identification of radiation-sensitivity gene association networks from time …

A Michna, H Braselmann, M Selmansberger, A Dietz… - PloS one, 2016 - journals.plos.org
Gene expression time-course experiments allow to study the dynamics of transcriptomic
changes in cells exposed to different stimuli. However, most approaches for the …

Non-negative matrix and tensor factorization based classification of clinical microarray gene expression data

Y Li, A Ngom - 2010 IEEE international conference on …, 2010 - ieeexplore.ieee.org
Non-negative information can benefit the analysis of microarray data. This paper
investigates the classification performance of non-negative matrix factorization (NMF) over …

Detection and interpretation of metabolite–transcript coresponses using combined profiling data

H Redestig, IG Costa - Bioinformatics, 2011 - academic.oup.com
Motivation: Studying the interplay between gene expression and metabolite levels can yield
important information on the physiology of stress responses and adaptation strategies …